Abstract
The receptors for the Il-3/IL-5/GM-CSF cytokine family are composed of a heterodimeric com-plex
of a cytokine-specific a chain and a common ß chain (ßc). Binding of IL-3/IL-5/GM-CSF to their respective
receptors rapidly induces activation of multiple intracellular signalling pathways, including the Ras-Raf-ERK, the
JAK/STAT, the phosphatidylinositol 3-kinase PKB, and the JNK/SAPK and p38
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