Abstract
Decades ago, in 1959, dopamine was found to be an essential neurotransmitter. In the years that followed, dopaminergic
neurotransmission turned out to be critical for normal motor-, motivational- and reward-related functions. Nowadays it is
known that dopaminergic signaling is not restricted to point-to-point synaptic contacts, but also involves volume transmission,
which requires synaptic
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