Abstract
Fc-receptors, such as FcaR and FcgRII,
play an important role in leukocyte activation,
and rapid modulation of ligand
binding (‘‘activation’’) is critical for receptor
regulation.We have previously demonstrated
that ligand binding to Fc-receptors
on human eosinophils is dependent
on cytokine stimulation. Utilization of
pharmacological inhibitors provided evidence
that the phenomenon of interleukin
(IL)-5 induced immunoglobulin A (IgA)
binding to human eosinophils
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