Molecular mechanisms of cytokine-mediated proliferation and survival / Pascale Francis Dijkers - [S.l.] : [s.n.], 2001 - Tekst. - Proefschrift Universiteit Utrecht

NBC: 44.45: immunologie

Trefwoorden: Apotosis, signal transduction, immunology, cytokines, cell cycle, Bcl-2, transcription

• Title
  
• Contents
  
• Chapter 1: Introduction
  
• Chapter 2: Regulation and Function of Protein Kinase B and MAP Kinase activation by the IL-3/IL-5/GM-CSF receptor
  
• Chapter 3: Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27KIP1
  
• Chapter 4: Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the Forkhead transcription factor FKHR-L1
  
• Chapter 5: FKHR-L1 is a critical effector of cell death induced by interleukin-3 withdrawal: PKB-mediated inhibition of FKHR-L1 activity enhances cell survival by maintenance of mitochondrial integrity
  
• Chapter 6: Identification of novel FKHR-L1 targets by gene array analysis
  
• Chapter 7: General discussion
  
• Nederlandse samenvatting
  
• Dankwoord
  
• Curriculum Vitae
  

• Volledig proefschrift (3.616 kB)