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Now showing items 821-840 of 40729

Data-efficient machine learning methods in the ME-TIME study: Rationale and design of a longitudinal study to detect atrial fibrillation and heart failure from wearables

Naseri, Arman; Tax, David; van der Harst, Pim; Reinders, Marcel; van der Bilt, Ivo (Elsevier, 2023-12)

Background: Smartwatches enable continuous and noninvasive time series monitoring of cardiovascular biomarkers like heart rate (from photoplethysmograms), step counter, skin temperature, et cetera; as such, they have promise ...
Transmural collaborative care model for cardiovascular risk management and medication review in patients using antipsychotics in primary care (TACTIC): A study protocol of an incomplete stepped wedge cluster randomized trial

Jakobs, Kirsti M.; van den Brule-Barnhoorn, Karlijn J.; van Lieshout, Jan; Janzing, Joost G.E.; Cahn, Wiepke; Kievit, Wietske; Teerenstra, Steven; van den Muijsenbergh, Maria; Biermans, Marion C.J.; Bischoff, Erik W.M.A. (Elsevier, 2025-04)

Background: It is well established that patients with severe mental illness and those treated with atypical antipsychotics (AAPs) are at an increased risk of cardiovascular disease. However, primary care currently lacks ...
A context-based approach to predict intelligibility of meaningful and nonsense words in interrupted noise: Model evaluation

van Schoonhoven, Jelmer; Rhebergen, Koenraad S.; Dreschler, Wouter A. (Acoustical Society of America, 2023-10-01)

The context-based Extended Speech Transmission Index (cESTI) by Van Schoonhoven et al. (2022) was successfully used to predict the intelligibility of meaningful, monosyllabic words in interrupted noise. However, it is not ...
Red blood cell pyruvate kinase properties in Townes and Berkeley sickle cell disease mouse models – Of mice and men

Traets, Marissa J.M.; Ruiter, Titine J.J.; Levine, Charles; Rijneveld, Anita W.; Jans, Judith J.; Alt, Carsten; Rab, Minke A.E.; Chen, Yu Wei; van Wijk, Richard; van Oirschot, Brigitte A. (Academic Press Inc., 2025-03)

Pyruvate kinase (PK), a key ATP-generating enzyme in glycolysis, is a target for novel sickle cell disease (SCD) therapies. Enhancing PK activity lowers 2,3-diphosphyglycerate (2,3-DPG), increases adenosine triphosphate ...
Next-generation Robotics in Otology: The HEARO Procedure

Tekin, Ahmet M.; Bleys, Ronald L.A.W.; Matulic, Marco; Assadi, Masoud Zoka; van de Heyning, Paul; Bahşi, İlhan; Topsakal, Vedat (2025-01)

BACKGROUND: In a world that is globalizing and centered on rapid communication, hearing impairment is one of the most common disabilities. The most effective and successful neural prosthesis in humans for treating the ...
Characterization of heterozygous and homozygous mouse models with the most common hypertrophic cardiomyopathy mutation MYBPC3c.2373InsG in the Netherlands

Hilderink, Sarah; Schuldt, Maike; Goebel, Max; Jansen, Valentijn J.; Manders, Emmy; Moorman, Stan; Dorsch, Larissa M.; van Steenbeek, Frank G.; van der Velden, Jolanda; Kuster, Diederik W.D. (Academic Press Inc., 2023-12)

Hypertrophic cardiomyopathy (HCM) is frequently caused by mutations in the cardiac myosin binding protein-C (cMyBP-C) encoding gene MYBPC3. In the Netherlands, approximately 25% of patients carry the MYBPC3c.2373InsG founder ...
Perceived educators’ roles in student well-being in higher education

Douwes, Rynke; Metselaar, Janneke; Pijnenborg, Gerdina Hendrika Maria; Boonstra, Nynke (Taylor and Francis Ltd., 2023)

This study addresses the role of teachers in students’ well-being in higher education, which has not been well defined in the literature. A qualitative study was conducted at a Dutch university of applied sciences. It ...
Western diet triggers cardiac dysfunction in heterozygous Mybpc3-targeted knock-in mice: A two-hit model of hypertrophic cardiomyopathy

Nollet, Edgar E.; Algül, Sila; Goebel, Max; Schlossarek, Saskia; van der Wel, Nicole N.; Jans, Judith J.M.; van de Wiel, Mark A.; Knol, Jaco C.; Pham, Thang V.; Piersma, Sander R.; de Goeij-de Haas, Richard; Hermans, Jill; van Klinken, Jan Bert; van Weeghel, Michel; Houtkooper, Riekelt H.; Carrier, Lucie; Jimenez, Connie R.; Kuster, Diederik W.D.; van der Velden, Jolanda (Elsevier, 2023-12)

Background and aim: Phenotypic expression of hypertrophic cardiomyopathy (HCM) and disease course are associated with unfavorable metabolic health. We investigated if Western diet (WD) feeding is sufficient to trigger ...
Direct Stenting versus Conventional Stenting in Patients with ST-Segment Elevation Myocardial Infarction—A COMPARE CRUSH Sub-Study

Vogel, Rosanne F.; Delewi, Ronak; Wilschut, Jeroen M.; Lemmert, Miguel E.; Diletti, Roberto; van Vliet, Ria; van der Waarden, Nancy W.P.L.; Nuis, Rutger Jan; Paradies, Valeria; Alexopoulos, Dimitrios; Zijlstra, Felix; Montalescot, Gilles; Angiolillo, Dominick J.; Krucoff, Mitchell W.; Van Mieghem, Nicolas M.; Smits, Pieter C.; Vlachojannis, Georgios J. (Multidisciplinary Digital Publishing Institute (MDPI), 2023-10)

Background: Direct stenting (DS) compared with conventional stenting (CS) after balloon predilatation may reduce distal embolization during percutaneous coronary intervention (PCI), thereby improving tissue reperfusion. ...
Outcome of Recurrent Tracheoesophageal Fistula Treatment After Esophageal Atresia Repair

van Stigt, Marit J.B.; Hut, Julia E.; Reuling, Ellen M.B.P.; Stokroos, Robert J.; Tytgat, Stefaan H.A.J.; Verweij, Johannes W.; Bittermann, Arnold J.N.; Lindeboom, Maud Y.A. (W.B. Saunders, 2025-04)

Introduction Recurrent Tracheoesophageal Fistula (rTEF) is a complication of Esophageal Atresia (EA) that can lead to severe respiratory symptoms. RTEF can be corrected via endotracheal treatment (ET) or surgical treatment ...
Mechanical Fractionation of Adipose Tissue—A Scoping Review of Procedures to Obtain Stromal Vascular Fraction

Schipper, Jan Aart M.; van Laarhoven, Constance J.H.C.M.; Schepers, Rutger H.; Tuin, A. Jorien; Harmsen, Marco C.; Spijkervet, Fred K.L.; Jansma, Johan; van Dongen, Joris A. (MDPI AG, 2023-10)

Clinical indications for adipose tissue therapy are expanding towards a regenerative-based approach. Adipose-derived stromal vascular fraction consists of extracellular matrix and all nonadipocyte cells such as connective ...
Improvement in the ability to have sex in patients with Peyronie's disease treated with Collagenase Clostridium histolyticum

Geelhoed, Jeannette P.; Wegelin, Olivier; Tromp, Ellen; de Boer, Bert Jan; de Jong, Igle Jan; Beck, Jack J.H. (John Wiley & Sons Inc., 2023-01)

Objective: To describe the results of intralesional Collagenase Clostridium histolyticum (CCH) treatment in patients with Peyronie's disease (PD) in real-world setting. PD is characterized by curvature of the erect penis ...
Core Concepts: Self-Controlled Designs in Pharmacoepidemiology

Bots, Sophie H.; Brown, Jeremy; Wong, Angel Y.S.; Martin, Ivonne; Douglas, Ian; Klungel, Olaf H.; Schultze, Anna (John Wiley & Sons Inc., 2025-01)

One of the key challenges in pharmacoepidemiological studies is that of uncontrolled confounding, which occurs when confounders are poorly measured, unmeasured or unknown. Self-controlled designs can help address this ...
Salpingectomy With Delayed Oophorectomy Versus Salpingo-Oophorectomy in BRCA1/2 Carriers: Three-Year Outcomes of a Prospective Preference Trial

Van Bommel, Majke H.D.; Steenbeek, Miranda P.; Inthout, Joanna; Van Garderen, Tessa; Harmsen, Marline G.; Arts-De Jong, Marieke; Maas, Angela H.E.M.; Prins, Judith B.; Bulten, Johan; Van Doorn, Helena C.; Mourits, Marian J.E.; Tros, Rachel; Zweemer, Ronald P.; Gaarenstroom, Katja N.; Slangen, Brigitte F.M.; Brood-Van Zanten, Monique M.A.; Vos, M. Caroline; Piek, Jurgen M.J.; van Lonkhuijzen, Luc R.C.W.; Apperloo, Mirjam J.A.; Coppus, Sjors F.P.J.; Hoogerbrugge, Nicoline; Hermens, Rosella P.M.G.; De Hullu, Joanne A. (Wiley-Blackwell, 2025-05)

Objective: To compare menopause-related quality of life (QoL) after risk-reducing salpingectomy (RRS) versus risk-reducing salpingo-oophorectomy (RRSO) until 3 years of post-surgery. Design: A prospective study (TUBA study) ...
Implementation of the Automated Medication Dispensing System–Early Lessons From Eswatini

Williams, Victor; Haumba, Samson; Ngwenya-Ngcamphalala, Fikile; Mafukidze, Arnold; Musarapasi, Normusa; Byarugaba, Hugben; Chiripashi, Simbarashe; Dlamini, Makhosazana; Maseko, Thokozani; Dlamini, Nkhosikhona Advocate; Nyapokoto, Clara; Kibwana, Sharon; Bongomin, Pido; Mazibuko, Sikhathele; Bhembe, Fortunate; Ojoo, Sylvia; Okello, Velephi; Bazira, Deus (Frontiers Media S. A., 2023)

Objectives: This article describes the implementation of an automated medication dispensing system (AMDS) in Eswatini to increase medication access and presents the early lessons from this implementation. Methods: The AMDS ...
Screening for Hepatitis C Virus Reinfection Using a Behaviour-Based Risk Score among Men Who Have Sex with Men with HIV: Results from a Case–Control Diagnostic Validation Study

Hage, Kris; van de Kerkhof, Marita; Boyd, Anders; Carson, Joanne M.; Newsum, Astrid M.; Matser, Amy; van der Valk, Marc; Brinkman, Kees; Arends, Joop E.; Lauw, Fanny N.; Rijnders, Bart J.A.; van Eeden, Arne; Martinello, Marianne; Matthews, Gail V.; Schinkel, Janke; Prins, Maria (MDPI AG, 2023-10)

We assessed the predictive capacity of the HCV-MOSAIC risk score, originally developed for primary early HCV infection, as a screening tool for HCV reinfection in 103 men who have sex with men (MSM) with HIV using data ...
The CineECG in ischemia localization in ST-elevation (equivalent) acute coronary syndromes

Gorgels, Anton P.M.; van der Schaaf, Iris; Kloosterman, Manon; van Dam, Peter M. (Churchill Livingstone, 2023-11-01)

Aim of the study: In this proof of concept study we aimed to visualize and quantify the injury vectors using the CineECG in representative examples of ST elevation acute myocardial infarction (STEMI) and STEMI-equivalent ...
Per- and polyfluoroalkyl substances (PFAS) exposure and thyroid cancer risk

van Gerwen, Maaike; Colicino, Elena; Guan, Haibin; Dolios, Georgia; Nadkarni, Girish N.; Vermeulen, Roel C.H.; Wolff, Mary S.; Arora, Manish; Genden, Eric M.; Petrick, Lauren M. (Elsevier, 2023-11)

Background: Although per- and polyfluoroalkyl substances (PFAS) exposure is a potential contributor to the increasing thyroid cancer trend, limited studies have investigated the association between PFAS exposure and thyroid ...
Colchicine and diabetes in patients with chronic coronary artery disease: insights from the LoDoCo2 randomized controlled trial

Mohammadnia, Niekbachsh; Los, Jan; Opstal, Tjerk S.J.; Fiolet, Aernoud T.L.; Eikelboom, John W.; Mosterd, Arend; Nidorf, Stefan M.; Budgeon, Charley A.; Tijssen, Jan G.P.; Thompson, Peter L.; Tack, Cees J.; Simsek, Suat; Bax, Willem A.; Cornel, Jan H.; El Messaoudi, Saloua (Frontiers Media S. A., 2023)

Introduction: Despite optimal treatment, patients with chronic coronary artery disease (CAD) and diabetes mellitus (DM) are at high risk of cardiovascular events, emphasizing the need for new treatment options. The Low-Dose ...
Sequencing before prescription for immunosuppressed patients

Zheng, Shuxuan; Lutters, Bart; Verduyn Lunel, Frans (Elsevier, 2023-10-28)

Now showing items 821-840 of 40729