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Now showing items 641-660 of 40729

Revealing the limitations of 10-year MACE observations: 20-year observed total cardiovascular burden in the EPIC-Norfolk study

van Trier, Tinka J; Snaterse, Marjolein; Dorresteijn, Jannick An; Bogaart, Manon van den; Scholte Op Reimer, Wilma Jm; Visseren, Frank Lj; Peters, Ron Jg; Jørstad, Harald T; Boekholdt, S Matthijs (BMJ Publishing Group, 2025-02-04)

BACKGROUND: Primary prevention strategies for cardiovascular disease (CVD) conventionally rely on 10-year risk estimates of major adverse cardiovascular events (MACE). However, communicating longer-term total CVD risk may ...
Adherence to safety guidelines on paediatric procedural sedation: The results of a nationwide survey under general paediatricians in the Netherlands

Leroy, Piet L.J.M.; Nieman, F. H.M.; Blokland-Loggers, H. E.; Schipper, D. M.; Zimmermann, L. J.I.; Knape, J. T.A. (BMJ Publishing Group, 2010-12)

Objectives: Following two fatal accidents during paediatric procedural sedation (PS), the authors investigated the level of adherence to established safety standards on PS in a nationwide cohort of fully trained general ...
European training curriculum in sedation for gastrointestinal endoscopy: Official position statement of the European Society of Gastrointestinal Endoscopy (ESGE) and the European Society of Gastroenterology and Endoscopy Nurses and Associates (ESGENA)

Dumonceau, J. M.; Riphaus, A.; Beilenhoff, U.; Vilmann, P.; Hornslet, P.; Aparicio, J. R.; Dinis-Ribeiro, M.; Giostra, E.; Ortmann, M.; Knape, J. T.A.; Ladas, S.; Paspatis, G.; Ponsioen, C. Y.; Racz, I.; Wehrmann, T.; Walder, B.; Sabbagh, L. C. (Georg Thieme Verlag, 2013)
A cis-regulatory element controls expression of histone deacetylase 9 to fine-tune inflammasome-dependent chronic inflammation in atherosclerosis

Asare, Yaw; Yan, Guangyao; Schlegl, Christina; Prestel, Matthias; van der Vorst, Emiel P C; Teunissen, Abraham J P; Aronova, Arailym; Tosato, Federica; Naser, Nawraa; Caputo, Julio; Prevot, Geoffrey; Azzun, Anthony; Wefers, Benedikt; Wurst, Wolfgang; Schneider, Melanie; Forne, Ignasi; Bidzhekov, Kiril; Naumann, Ronald; van der Laan, Sander W; Brandhofer, Markus; Cao, Jiayu; Roth, Stefan; Malik, Rainer; Tiedt, Steffen; Mulder, Willem J M; Imhof, Axel; Liesz, Arthur; Weber, Christian; Bernhagen, Jürgen; Dichgans, Martin (Cell Press, 2025-03-11)

Common genetic variants in a conserved cis-regulatory element (CRE) at histone deacetylase (HDAC)9 are a major risk factor for cardiovascular disease, including stroke and coronary artery disease. Given the consistency of ...
Mo has a cough and is short of breath

Grant, Matthew; Honigh, Jonathan (Royal Australian College of General Practitioners, 2024-06-01)
The association of HIV status and depressive symptoms in the Ndlovu Cohort study

den Boer, Li Xiang Y.; Scheuermaier, Karine; Tempelman, Hugo A.; Barth, Roos E.; Devillé, Walter L. J. M.; Coutinho, Roel A.; Grobbee, Diederick E.; Venter, Francois; Vos-Seda, Alinda G.; Klipstein-Grobusch, Kerstin (Nature Publishing Group, 2025-02-06)

HIV majorly contributes to the disease burden in South Africa. Depressive symptoms are common in people living with HIV (PLHIV). Few studies compared depressive symptoms between PLHIV and those without HIV. The aim of the ...
Reply to Letter to the Editor on “Contrast-Enhanced Ultrasound Imaging Following Transperineal Laser Ablation for Lower Urinary Tract Symptoms”

van Kollenburg, Rob; van Riel, Luigi; de Reijke, Theo; van Leeuwen, Ton; de Bruin, Martijn; Oddens, Jorg (Elsevier, 2025-04)
Clinical subtypes in critically ill patients with sepsis: validation and parsimonious classifier model development

van Amstel, Rombout B E; Rademaker, Emma; Kennedy, Jason N; Bos, Lieuwe D J; Peters-Sengers, Hessel; Butler, Joe M; Bruse, Niklas; Dongelmans, Dave A; Kox, Matthijs; Vlaar, Alexander P J; van der Poll, Tom; Cremer, Olaf L; Seymour, Christopher W; van Vught, Lonneke A (Springer Science + Business Media, 2025-02-04)

Background: The application of sepsis subtypes to enhance personalized medicine in critically ill patients is hindered by the lack of validation across diverse cohorts and the absence of a simple classification model. We ...
Increased Levels of Inflammatory Proteins, Including TARC/CCL17, in Skin of AD Patients During JAK Inhibitor Treatment

Boesjes, Celeste M; van der Gang, Lian F; Bakker, Daphne S; den Hartog Jager, C F; de Graaf, Marlies; de Bruin-Weller, Marjolein S; van Wijk, Femke; Knol, Edward F (Wiley-Blackwell, 2025-03)
Ameloblastic Fibro-Odontoma with an FGFR1 Mutation: A Case Report

Aouam, Oumaima; Janssen, Nard G; de Leng, Wendy W J; Breimer, Gerben E (Humana Press, 2025-02-05)

PURPOSE: Ameloblastic fibro-odontoma (AFO) is a rare benign mixed odontogenic tumor that, after being classified for years as a distinct entity, was redefined as a "developing odontoma" in the 2017 World Health Organization ...
Advancing treatment response prediction in first-episode psychosis: integrating clinical and electroencephalography features

Dominicus, Livia; Zandstra, Melissa; Franse, Josephine; Otte, Wim; Hillebrand, Arjan; de Graaf, Simone; Ambrosen, Karen; Glenthøj, Birte Yding; Zalesky, Andrew; Borup Bojesen, Kirsten; Sørensen, Mikkel; Scheepers, Floortje; Stam, Cornelis; Oranje, Bob; Ebdrup, Bjorn; van Dellen, Edwin (Wiley-Blackwell, 2025-04)

AIMS: Prompt diagnosis and intervention are crucial for first-episode psychosis (FEP) outcomes, but predicting the response to antipsychotics remains challenging. We studied whether adding electroencephalography (EEG) ...
Tissue-specific modulation of CRISPR activity by miRNA-sensing guide RNAs

Garcia-Guerra, Antonio; Sathyaprakash, Chaitra; De Jong, Olivier G.; Lim, Wooi F.; Vader, Pieter; El Andaloussi, Samir; Bath, Jonathan; Reine, Jesus; Aoki, Yoshitsugu; Turberfield, Andrew J.; Wood, Matthew J.A.; Rinaldi, Carlo (Oxford University Press, 2025-01-27)

Nucleic acid nanostructures offer unique opportunities for biomedical applications due to their sequence-programmable structures and functions, which enable the design of complex responses to molecular cues. Control of the ...
The interplay between mitochondrial DNA genotypes, female infertility, ovarian response, and mutagenesis in oocytes

Van Der Kelen, Annelore; Li Piani, Letizia; Mertens, Joke; Regin, Marius; Couvreu De Deckersberg, Edouard; Van De Velde, Hilde; Sermon, Karen; Tournaye, Herman; Verpoest, Willem; Hes, Frederik Jan; Blockeel, Christophe; Spits, Claudia (2025-01)

STUDY QUESTION: Is there an association between different mitochondrial DNA (mtDNA) genotypes and female infertility or ovarian response, and is the appearance of variants in the oocytes favored by medically assisted ...
The association between hospital volume and overall survival in adult AML patients treated with intensive chemotherapy

Kaplan, Z. L.R.; van Leeuwen, N.; van Klaveren, D.; Eijkenaar, F.; Visser, O.; Posthuma, E. F.M.; Zweegman, S.; Huls, G.; van Rhenen, A.; Blijlevens, N. M.A.; Cornelissen, J. J.; van de Loosdrecht, A. A.; Pruijt, J. H.F.M.; Levin, M. D.; Hoogendoorn, M.; Lemmens, V. E.P.P.; Lingsma, H. F.; Dinmohamed, A. G. (Elsevier, 2025-02)

Background: Acute myeloid leukemia (AML) requires specialized care, particularly when administrating intensive remission induction chemotherapy (ICT). High-volume hospitals are presumed more adept at delivering this complex ...
PEGylated Granulocyte Colony-Stimulating Factor and Plerixafor Enhance Autologous Stem and Progenitor Cell Mobilization and Transplantation in Pediatric Patients

Hochheuser, Caroline; Rozeman, Maria L.; Kunze, Nina; Gelineau, Nina U.; Kuijk, Carlijn; Jaspers-Bakker, Antoinette; van den Bos, Cor; Dierselhuis, Miranda P.; Slager, Tirza J.E.; Fiocco, Marta; Zsiros, József; Tissing, Wim J.E.; Westinga, Kasper; Zwaan, Christian M.; Voermans, Carlijn; Tytgat, Godelieve A.M.; Kraal, Kathelijne C.J.M.; Timmerman, Ilse (Mary Ann Liebert Inc., 2025-02)

Autologous hematopoietic stem cell transplantation is used to restore bone marrow function after high-dose chemotherapy. For apheresis, granulocyte colony-stimulating factor (G-CSF) is standard of care, but obtaining ...
Xolography for Biomedical Applications: Dual-Color Light-Sheet Printing of Hydrogels With Local Control Over Shape and Stiffness

Stoecker, Lena; Cedillo-Servin, Gerardo; König, Niklas F.; de Graaf, Freek V.; García-Jiménez, Marcela; Hofmann, Sandra; Ito, Keita; Wentzel, Annelieke S.; Castilho, Miguel (Wiley-Blackwell, 2025-03)

Current challenges in tissue engineering include creation of extracellular environments that support and interact with cells using biochemical, mechanical, and structural cues. Spatial control over these cues is currently ...
Pembrolizumab versus chemotherapy in microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer: 5-year follow-up from the randomized phase III KEYNOTE-177 study

André, T.; Shiu, K. K.; Kim, T. W.; Jensen, B. V.; Jensen, L. H.; Punt, C. J.A.; Smith, D.; Garcia-Carbonero, R.; Alcaide-Garcia, J.; Gibbs, P.; de la Fouchardiere, C.; Rivera, F.; Elez, E.; Le, D. T.; Yoshino, T.; Zuo, Y.; Fogelman, D.; Adelberg, D.; Diaz, L. A. (Oxford University Press, 2025-03)

Background: Results from the phase III KEYNOTE-177 study established pembrolizumab as a new first-line standard of care for microsatellite instability-high or mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal ...
Communicating a Pediatric Leukemia Diagnosis to a Child and Their Family: A Qualitative Study into Oncologists’ Perspectives

Buursma, Petra; Schepers, Sasja A.; Zwerus, Daniël; Alkirawan, Rima; van den Bergh, Esther M.M.; Dors, Natasja; Hoogerbrugge, Peter M.; Grootenhuis, Martha A.; Kars, Marijke C. (Wiley-Liss Inc., 2025-04)

Background: A pediatric cancer diagnosis is overwhelming and stressful for the whole family. Patient-centered communication during the diagnostic conversation can support medical and psychosocial adaptation to the disease. ...
Incorporating Spatial and Spectral Saturation Modules Into MR Fingerprinting

Trimble, Christopher G; Sørland, Kaia I; Wu, Chia Yin; van Riel, Max HC; Bathen, Tone F; Elschot, Mattijs; Cloos, Martijn A (John Wiley & Sons Inc., 2025-03)

In this work, we introduce spatial and chemical saturation options for artefact reduction in magnetic resonance fingerprinting (MRF) and assess their impact on T1 and T2 mapping accuracy. An existing radial MRF pulse ...
Supervised Exercise for Patients With Metastatic Breast Cancer: A Cost-Utility Analysis Alongside the PREFERABLE-EFFECT Randomized Controlled Trial

Schouten, Aniek E.M.; Hiensch, Anouk E.; Frederix, Geert W.J.; Monninkhof, Evelyn M.; Schmidt, Martina E.; Clauss, Dorothea; Gunasekara, Nadira; Belloso, Jon; Trevaskis, Mark; Rundqvist, Helene; Wiskemann, Joachim; Müller, Jana; Sweegers, Maike G.; Fremd, Carlo; Altena, Renske; Bijlsma, Rhodé M.; Sonke, Gabe; Lahuerta, Ainhara; Mann, G. Bruce; Francis, Prudence A.; Richardson, Gary; Malter, Wolfram; Kufel-Grabowska, Joanna; Van Der Wall, Elsken; Aaronson, Neil K.; Senkus, Elzbieta; Urruticoechea, Ander; Zopf, Eva M.; Bloch, Wilhelm; Stuiver, Martijn M.; Wengstrom, Yvonne; Steindorf, Karen; Van Der Meulen, Miriam P.; May, Anne M. (Lippincott Williams & Wilkins, 2025-04-10)

PURPOSETo evaluate the cost utility of a 9-month supervised exercise program for patients with metastatic breast cancer (mBC), compared with control (usual care, supplemented with general activity advice and an activity ...

Now showing items 641-660 of 40729