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Narrative review of the efficacy and safety of the high-concentration (179mg) capsaicin patch in peripheral neuropathic pain with recommendations for clinical practice and future research

Freynhagen, Rainer; Baron, Ralf; Huygen, Frank; Perrot, Serge (Lippincott Williams & Wilkins, 2025-04)

High-concentration capsaicin patch (HC capsaicin patch) is a locally acting treatment option for adults with peripheral neuropathic pain (pNeP) of various etiologies. Numerous clinical trials, post hoc analyses, and ...
Update on Cancer Screening in Children with Syndromes of Bone Lesions, Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome, and Other Rare Syndromes

Michaeli, Orli; Kim, Sun Young; Mitchell, Sarah G.; Jongmans, Marjolijn C.J.; Wasserman, Jonathan D.; Perrino, Melissa R.; Das, Anirban; MacFarland, Suzanne P.; Scollon, Sarah R.; Greer, Mary Louise C.; Sobreira, Nara; Gallinger, Bailey; Lupo, Philip J.; Malkin, David; Schneider, Kami Wolfe; Schultz, Kris Ann P.; Foulkes, William D.; Woodward, Emma R.; Stewart, Douglas R. (2025-02-01)

The management of children with syndromes associated with an increased risk of benign and malignant neoplasms is a complex challenge for health care professionals. The 2023 American Association for Cancer Research Childhood ...
The prognostic and predictive value of the luminal-like subtype in hormone receptor-positive breast cancer: an analysis of the DATA trial

Lammers, S. W.M.; Geurts, S.M.E.; Hermans, K.E.P.E.; Kooreman, L. F.S.; Swinkels, A. C.P.; Smorenburg, C. H.; van der Sangen, M. J.C.; Kroep, J. R.; Honkoop, A. H.; van den Berkmortel, F. W.P.J.; de Roos, W. K.; Linn, S. C.; Imholz, A. L.T.; Vriens, I. J.H.; Tjan-Heijnen, V. C.G. (Elsevier, 2025-02)

Background: This study determines the prognostic value of the luminal-like subtype in patients with hormone receptor-positive breast cancer and explores whether the efficacy of extended anastrozole therapy differs between ...
From responsibility to responsibilization in stem cell research: An ethical framework

Assen, Lars S.; Bredenoord, Annelien L.; Isasi, Rosario; Fabbri, Morris A.; Tryfonidou, Marianna A.; Jongsma, Karin R. (Cell Press, 2025-02-11)

Adopting a responsibilization approach can further improve the ethical conduct of stem cell (SC) research and applications. This approach helps align new and existing solutions for ethical implications by focusing on ...
Hypothyroid-induced hyponatraemia in a premature infant with a false-negative newborn screening for congenital hypothyroidism

Van Gisbergen, Maartje; De Moor, Ronald; Verrijn Stuart, Annemarie; Van Den Berg, Gerrit; Sijbesma, Bianco; Van Hoften, Jacorina (BMJ Publishing Group, 2025-01-31)

Worldwide newborn screening (NBS) programmes detect one in 2000-4000 newborns with forms of congenital hypothyroidism (CH). However, some newborns such as premature born babies, are at increased risk for a false-negative ...
Niche-inspired collagen infused melt electrowritten scaffolds for craniofacial bone regeneration

Daghrery, Arwa; Dal-Fabbro, Renan; Xu, Jinping; Kaigler, Darnell; de Ruijter, Mylène; Gawlitta, Debby; Malda, Jos; Bottino, Marco C. (Elsevier, 2025-05)

Advances in tissue engineering are focused on devising improved therapeutics to reconstruct craniofacial bones. In cell-based strategies, biomaterials with specific physicochemical properties can mimic natural environments, ...
Dose-volume parameter evaluation of a sub-fractionation workflow for adaptive radiotherapy of prostate cancer patients on a 1.5 T magnetic resonance imaging radiotherapy system

Tsekas, Georgios; Zachiu, Cornel; Bol, Gijsbert H.; van der Voort van Zyp, Jochem R.N.; van de Pol, Sandrine M.G.; de Boer, Johannes C.J.; Raaymakers, Bas W. (Elsevier, 2025-01)

Background and purpose: This study focuses on evaluating a sub-fractionation workflow for intrafraction motion mitigation of prostate cancer patients on a 1.5 T magnetic resonance imaging radiotherapy system. Materials and ...
Hybrid cellular automata-based air pollution model for traffic scenario microsimulations

Sonnenschein, Tabea S.; Yuan, Zhendong; Khan, Jibran; Kerckhoffs, Jules; Vermeulen, Roel C.H.; Scheider, Simon (Elsevier Limited, 2025-03)

Scenario microsimulations like agent-based models can account for feedbacks and spatio-temporal and social heterogeneity when projecting future intervention impacts. Addressing air pollution exposure requires traffic ...
Long-term outcomes in five patients with autoimmune pulmonary alveolar proteinosis treated with molgramostim inhalation solution

Montaño, Celia; Bendstrup, Elisabeth; Rønnov-Jessen, Ida; Salgado, Sara; Sterniste, Georg; Valipour, Arschang; Veltkamp, Marcel; Molina-Molina, Maria (European Respiratory Society, 2025-01)
Family Screening in Patients With Dilated and Arrhythmogenic Cardiomyopathy: The Road Toward Gene-Specific Recommendations

Stroeks, Sophie L.V.M.; Muller, Steven; Beelen, Nina J.; Venner, Max F.G.H.M.; Baas, Annette F.; van Empel, Vanessa P.M.; Krapels, Ingrid P.C.; Hazebroek, Mark R.; te Riele, Anneline S.J.M.; Verdonschot, Job A.J. (Lippincott Williams & Wilkins, 2025-02)
Celebrating a quinquennium of the EJCN Methods Corner

Denfeld, Quin E.; Ferguson, Caleb; Lee, Christopher S.; Jaarsma, Tiny; Moons, Philip (Elsevier, 2025-01)
Preoperative stereotactic radiotherapy to prevent pancreatic fistula in high-risk patients undergoing pancreatoduodenectomy (FIBROPANC): prospective multicentre phase II single-arm trial

Wismans, Leonoor V.; Hendriks, Tessa E.; Suurmeijer, J. Annelie; Nuyttens, Joost J.; Bruynzeel, Anna M.; Intven, Martijn P.; van Driel, Lydi M.; Haen, Roel; de Wilde, Roeland F.; Koerkamp, Bas Groot; Busch, Olivier R.; Stoker, Jaap; Verheij, Joanne; Farina, Arantza; de Boer, Onno J.; Doukas, Michail; de Hingh, Ignace H.; Lips, Daan J.; van der Harst, Erwin; van Tienhoven, Geertjan; van Eijck, Casper H.; Besselink, Marc G. (John Wiley & Sons Inc., 2025-02-01)

Background: Postoperative pancreatic fistula is the main driver of morbidity and mortality after pancreatoduodenectomy. In high-risk patients, the rate of postoperative pancreatic fistula approaches 50%, whereas it is below ...
Fusobacterium nucleatum upregulates the immune inhibitory receptor PD-L1 in colorectal cancer cells via the activation of ALPK1

Duizer, Coco; Salomons, Moniek; van Gogh, Merel; Gräve, Sanne; Schaafsma, Freke A.; Stok, Maaike J.; Sijbranda, Merel; Kumarasamy Sivasamy, Raghuvandhanan; Willems, Rob J.L.; de Zoete, Marcel R. (Landes Bioscience, 2025-12)

Fusobacterium nucleatum is a Gram-negative oncobacterium that is associated with colorectal cancer. The molecular mechanisms utilized by F. nucleatum to promote colorectal tumor development have largely focused on ...
Three-dimensional assessment of ascending aortic stiffness, motion, and growth in ascending thoracic aortic aneurysm

Tjahjadi, Nicasius S; Kim, Taeouk; Marway, Prabhvir S; Jorge, Carlos Alberto Campello; Baker, Timothy J; Hazenberg, Constantijn; van Herwaarden, Joost A; Patel, Himanshu J; Figueroa, C Alberto; Burris, Nicholas S (2025-01)

AIMS: Aortic wall stiffening in ascending thoracic aortic aneurysm (aTAA) is common. However, the spatial and temporal relationships between stiffness, aortic size, and growth in aTAA remain unclear. METHODS AND RESULTS: ...
Interlaboratory assays from the fungal PCR Initiative and the Modimucor Study Group to improve qPCR detection of Mucorales DNA in serum: one more step toward standardization

Rocchi, Steffi; Scherer, Emeline; White, P Lewis; Guitton, Audrey; Alanio, Alexandre; Botterel, Françoise; Bougnoux, Marie Elisabeth; Buitrago, Maria José; Cogliati, Massimo; Cornu, Marjorie; Damiani, Celine; Denis, Julie; Dupont, Damien; Fuchs, Stefan; Gorton, Rebecca; Haas, Pieter-Jan; Hagen, Ferry; Hare, Rasmus; Iriart, Xavier; Klaassen, Corné H W; Lackner, Michaela; Lengerova, Martina; Melchers, Willem J G; Morio, Florent; Poirier, Philippe; Springer, Jan; Valot, Stephane; Willinger, Birgit; Mazzi, Cristina; Cruciani, Mario; Barnes, Rosemary; Donnelly, J Peter; Loeffler, Jürgen; Millon, Laurence (American Society for Microbiology, 2025-02-19)

The aim of this study was to identify parameters influencing DNA extraction and PCR amplification efficiencies in an attempt to standardize Mucorales qPCR. The Fungal PCR Initiative Mucorales Laboratory Working Group ...
C21ORF2 mutations point towards primary cilia dysfunction in amyotrophic lateral sclerosis

De Decker, Mathias; Zelina, Pavol; Moens, Thomas G; Beckers, Jimmy; Contardo, Matilde; Dittlau, Katarina Stoklund; Van Schoor, Evelien; Ronisz, Alicja; Eggermont, Kristel; Moisse, Matthieu; Chandran, Siddharthan; Veldink, Jan H; Thal, Dietmar Rudolf; Van Den Bosch, Ludo; Pasterkamp, R Jeroen; Van Damme, Philip (Oxford University Press, 2025-03-06)

Progressive loss of motor neurons is the hallmark of the neurodegenerative disease amyotrophic lateral sclerosis (ALS), but the underlying disease mechanisms remain incompletely understood. In this study, we investigate ...
Development and validation of a gonadotropin dose selection model for optimized ovarian stimulation in IVF/ICSI: an individual participant data meta-analysis

Schouten, Nienke; Wang, Rui; Torrance, Helen; Van Tilborg, Theodora; Bastu, Ercan; Bergh, Christina; D'Hooghe, Thomas; Friis Petersen, Jesper; Jayaprakasan, Kannamannadiar; Khalaf, Yacoub; Klinkert, Ellen; La Marca, Antonio; Vuong, Lan; Lapensée, Louise; Lensen, Sarah; Magnusson, Åsa; Allegra, Adolfo; Nyboe Andersen, Anders; Oudshoorn, Simone; Popovic-Todorovic, Biljana; Mol, Ben Willem; Eijkemans, Marinus; Broekmans, Frank (Oxford University Press, 2025-03-01)

BACKGROUND: The ovarian response to gonadotropin stimulation varies widely among women, and could impact the probability of live birth as well as treatment risks. Many studies have evaluated the impact of different ...
Surviving transition: A qualitative case study on how families adapt as their youth with medical complexity transitions from child to adult systems of care

Li, Lin; Carter, Nancy; Gorter, Jan Willem; Till, Linda; White, Marcy; Strachan, Patricia H (Elsevier, 2024-01)

BACKGROUND: A growing population of youth with medical complexity (YMC) are entering adult health care, education, and social systems in which their needs have been largely neglected. To better support YMC and their families, ...
Enteropathy-associated T-cell lymphoma: A population-based cohort study on incidence, treatment, and outcome in the Netherlands

Meeuwes, Frederik O; Brink, Mirian; Plattel, Wouter J; Vermaat, Joost S P; Kersten, Marie José; Wondergem, Mariëlle; Visser, Otto; van der Poel, Marjolein W M; Oostvogels, Rimke; Woei-A-Jin, F J Sherida H; Böhmer, Lara; Snijders, Tjeerd J F; Huls, Gerwin A; Nijland, Marcel (2024-12)

INTRODUCTION: Enteropathy-associated T-cell lymphoma (EATL) is a peripheral T-cell lymphoma (PTCL) with a poor prognosis. Cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) with or without etoposide consolidated ...
Exploring the association of metabolic factors and chronic musculoskeletal pain over a period of 10 years - the Doetinchem Cohort Study

Meert, Lotte; Picavet, H Susan J; Vervullens, Sophie; Meeus, Mira; Van Kuijk, Sander M J; Verschuren, W M Monique; Smeets, Rob J E M (Springer Science and Business Media Deutschland GmbH, 2025-02)

Objective: To examine (a) the association between metabolic factors and chronic musculoskeletal pain (CMP), (b) metabolic predictors of CMP 10 years later, and (c) the association and evolution of metabolic factors across ...

Now showing items 541-560 of 40729