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UMC Repository: Recent submissions

  • When, where, who, what, and why? The five Ws of workflow analysis for implementing an AI decision support tool at the intensive care 
    de Hond, Anne A.H.; Vosslamber, Suzanne; Lange, Sanne; Engel, Friso; Lindhout, Mette; Noorlag, Puck; Steyerberg, Ewout W.; Cinà, Giovanni; Arbous, M. Sesmu (2025-06)
    Background: There has been a surge in the development of clinical artificial intelligence (AI) decision support tools. Yet, few of these tools have been implemented into clinical practice. A lack of understanding of the ...
  • Computational modeling of peritoneal dialysis: An overview 
    Swapnasrita, Sangita; de Vries, Joost C.; Öberg, Carl M.; Carlier, Aurélie M.F.; Gerritsen, Karin G.F. (American Institute of Mathematical Sciences, 2025-02-13)
    Peritoneal dialysis (PD) is a kidney replacement therapy for patients with end-stage renal disease. It is becoming more popular as a result of a rising interest in home dialysis. Its effectiveness depends on several ...
  • Designing an online BCI forum: insights from researchers and end-users 
    Ziebell, Philipp; Modde, Aurélie; Roland, Ellen; Eidel, Matthias; Vansteensel, Mariska J.; Mrachacz-Kersting, Natalie; Vaughan, Theresa M.; Kübler, Andrea (IOP Publishing Ltd., 2025-02-20)
    Objective. Brain-computer interfaces (BCIs) can support non-muscular communication and device control for severely paralyzed people. However, efforts that directly involve potential or actual end-users and address their ...
  • Cost-effectiveness of cranial implants compared with autologous bone grafts 
    Klieverik, Vita M.; Robe, Pierre A.; Muradin, Marvick S.M.; Woerdeman, Peter A. (Elsevier, 2025-01)
    Introduction: Autografts are considered more cost-effective than cranial implants due to the use of the patient's own bone. However, autografts are associated with a higher revision surgery rate because of their intrinsic ...
  • Finding Consensus on Trust in AI in Health Care: Recommendations From a Panel of International Experts 
    Starke, Georg; Gille, Felix; Termine, Alberto; Aquino, Yves Saint James; Chavarriaga, Ricardo; Ferrario, Andrea; Hastings, Janna; Jongsma, Karin; Kellmeyer, Philipp; Kulynych, Bogdan; Postan, Emily; Racine, Elise; Sahin, Derya; Tomaszewska, Paulina; Vold, Karina; Webb, Jamie; Facchini, Alessandro; Ienca, Marcello (Journal of medical Internet Research, 2025-02-19)
    Background: The integration of artificial intelligence (AI) into health care has become a crucial element in the digital transformation of health systems worldwide. Despite the potential benefits across diverse medical ...
  • The prevalence and determinants of alcohol use in the adult population of Tehran: insights from the Tehran Cohort Study (TeCS) 
    Shafiee, Akbar; Toreyhi, Hossein; Hosseini, Seyedayin; Heidari, Amirhossein; Jalali, Arash; Mohammadi, Mohammad; Alaeddini, Farshid; Saadat, Soheil; Sadeghian, Saeed; Boroumand, Mohamamdali; Karimi, Abbasali; Franco, Oscar H. (Springer Science and Business Media Deutschland GmbH, 2025-02-18)
    Background: Although alcohol has been illegal in Iran for over four decades, its consumption persists. This study aims to determine the prevalence and determinants of alcohol consumption in Tehran, the Middle East’s ...
  • Advancing risk stratification in kidney transplantation: integrating HLA-derived T-cell epitope and B-cell epitope matching algorithms for enhanced predictive accuracy of HLA compatibility 
    Niemann, Matthias; Matern, Benedict M.; Gupta, Gaurav; Tanriover, Bekir; Halleck, Fabian; Budde, Klemens; Spierings, Eric (Frontiers Media S. A., 2025-02-11)
    Introduction: The immune-mediated rejection of transplanted organs is a complex interplay between T cells and B cells, where the recognition of HLA-derived epitopes plays a crucial role. Several algorithms of molecular ...
  • Lessons learned from a candidate gene study investigating aromatase inhibitor treatment outcome in breast cancer 
    Hoppe, Reiner; Winter, Stefan; Lo, Wing Yee; Michailidou, Kyriaki; Bolla, Manjeet K.; Keeman, Renske; Wang, Qin; Dennis, Joe; Lush, Michael; Kalari, Krishna R.; Goetz, Matthew P.; Wang, Liewei; Cairns, Junmei; Weinshilboum, Richard; Shepherd, Lois; Chen, Bingshu E.; Häberle, Lothar; Ruebner, Matthias; Beckmann, Matthias W.; He, Wei; Larson, Nicole L.; Armasu, Sebastian M.; Schroth, Werner; Chowbay, Balram; Khor, Chiea Chuen; Abubakar, Mustapha; Antoniou, Antonis C.; Brüning, Thomas; Castelao, Jose E.; Chang-Claude, Jenny; NBCS Collaborators, Collaborators; Dörk, Thilo; Eccles, Diana M.; Figueroa, Jonine D.; Gago-Dominguez, Manuela; García-Sáenz, José A.; Gündert, Melanie; Hack, Carolin C.; Hamann, Ute; Han, Sileny; Hooning, Maartje J.; Huebner, Hanna; ABCTB Investigators, Investigators; John, Esther M.; Ko, Yon Dschun; Kristensen, Vessela N.; Linn, Sabine; Margolin, Sara; Mavroudis, Dimitrios; Nevanlinna, Heli; Neven, Patrick; Obi, Nadia; Park-Simon, Tjoung Won; Pylkäs, Katri; Rashid, Muhammad U.; Romero, Atocha; Saloustros, Emmanouil; Sawyer, Elinor J.; Tapper, William J.; Tomlinson, Ian; Wendt, Camilla; Winqvist, Robert; Dunning, Alison M.; Simard, Jacques; Hall, Per; Pharoah, Paul D.P.; Schwab, Matthias; Couch, Fergus J.; Czene, Kamila; Fasching, Peter A.; Easton, Douglas F.; Schmidt, Marjanka K.; Ingle, James N.; Brauch, Hiltrud (Elsevier, 2025-02-19)
    The role of germline genetics in adjuvant aromatase inhibitor (AI) treatment efficacy in ER-positive breast cancer is poorly understood. We employed a two-stage candidate gene approach to examine associations between ...
  • Post pubertal outcome after use of oral mucosa in urethral reconstruction for hypospadias in prepubertal boys: a systematic review 
    Tsachouridis, George; Nijman, Rien; de Kort, Laetitia M.O.; de Graaf, Petra (Springer-Verlag, 2025-02-13)
    Oral mucosa graft urethroplasty (OMGU) is a surgical technique used in complex hypospadias repair. However, long-term outcomes in prepubertal boys, particularly through and after puberty, are not well established. To ...
  • Exposure to clinical stressors during NICU admission in preterm infants 
    Meesters, Naomi J.; van den Bosch, Gerbrich E.; Tataranno, Maria Luisa; van den Akker, Chris H.P.; van Ganzewinkel, Christ Jan; Barge, Judith A.Ten; Schuerman, Frank A.B.A.; van Zanten, Henriette; de Boode, Willem P.; Raets, Marlou M.A.; Dijk, Peter H.; van Rosmalen, Joost; Vermeulen, Marijn J.; Onland, Wes; Haverman, Lotte; Reiss, Irwin K.M.; van Kaam, Anton H.; Benders, Manon; van Dijk, Monique; Simons, Sinno H.P.; HIPPO study group (Springer-Verlag, 2025-02-13)
    This study aims to quantify stress exposure related to clinical stressors in preterm infants during NICU admission and identify risk factors for high stress exposure. In this national cohort study, preterm infants (gestational ...
  • Healthy lifestyle factors and combined macrovascular and microvascular events in diabetes patients with high cardiovascular risk: results from ADVANCE 
    You, Shoujiang; Zheng, Danni; Wang, Yanan; Li, Qiang; Nguyen, Tu N.; Peters, Ruth; Chen, Xiaoying; Wang, Xia; Cao, Yongjun; Grobbee, Diederick E.; Harrap, Stephen; Mancia, Giuseppe; Williams, Bryan; Poulter, Neil R.; Lisheng, Liu; Marre, Michel; Hamet, Pavel; Anderson, Craig S.; Woodward, Mark; Chalmers, John; Harris, Katie (BioMed Central Ltd., 2025-02-12)
    Background: To explore whether healthy lifestyle factors (HLFs) predict a lower risk of major macrovascular and microvascular events and death in people with type 2 diabetes (T2D) with a high risk of vascular complications. ...
  • The positive impact of a quality improvement collaborative on process indicators for geriatric hip fracture care 
    Coeckelberghs, Ellen; Seys, Deborah; Lens, Charlotte; Vanhaecht, Kris; Claessens, Fien; Weltens, Caroline; De Ridder, Dirk; Depuydt, Eline; De Weerdt, Wim; De Baets, Thierry; Eysackers, Jessy; Hermans, Stijn; Herteleer, Michiel; Leirs, Geert; Lynen, Sofie; Matthys, Frederik; Molenaers, Ben; Mulliez, Alexander; Pattyn, Christophe; Somers, Jan; Tengrootenhuysen, Mike; Vanderkerckhove, Maxence; Van Esbroeck, Marleen; Van Hecke, Kyri; Van Hove, Eline; Nijs, Stefaan; Sermon, An (Springer London, 2025-02-12)
    Summary: Adherence to guidelines for geriatric patients with a hip fracture is challenging. With this study, adherence to important quality indicators in geriatric hip fracture care was improved. A quality improvement ...
  • Rationale, implementation considerations, delineation and planning target objective recommendations for volumetric modulated arc therapy and helical tomotherapy total body irradiation, total marrow irradiation, total marrow and lymphoid irradiation and total lymphoid irradiation 
    Hoeben, Bianca A.W.; Saldi, Simonetta; Aristei, Cynthia; Engellau, Jacob; Ocanto, Abrahams; Hiniker, Susan M.; Misson-Yates, Sarah; Kobyzeva, Daria A.; Pazos, Montserrat; George Mikhaeel, N.; Rodriguez-Roldan, Marta; Seravalli, Enrica; Bosman, Mirjam E.; Han, Chunhui; Losert, Christoph; Engström, Per E.; Fulcheri, Christian P.L.; Zucchetti, Claudio; Ferrer, Carlos; Hussein, Mohammad; Loginova, Anna A.; Clark, Catharine H.; Wong, Jeffrey Y.C. (Elsevier Ireland Ltd, 2025-05)
    As a component of myeloablative conditioning before allogeneic hematopoietic stem cell transplantation (HSCT), Total Body Irradiation (TBI) is employed in radiotherapy centers all over the world. In recent and coming years, ...
  • Screening and care for emotional and cognitive problems after stroke: A prospective mixed-methods process evaluation of a cluster-randomized controlled trial 
    Slenders, J. P.L.; Visser-Meilij, JM Anne; Kwa, V.I.H.; van den Berg - Vos, R.M.; Sommers-Spijkerman, Marion; van Heugten, C.M. (BioMed Central, 2025-03-05)
    BACKGROUND: Emotional and cognitive problems are prevalent after stroke. We developed an intervention including screening for emotional and cognitive problems, screening for participation restrictions, self-management ...
  • High-throughput approaches for the identification of ribosome heterogeneity 
    Kyei-Baffour, Edwin S; Lin, Qi Chang; Alkan, Ferhat; Faller, William J (Royal Society Publishing, 2025-03-06)
    Recent advances in the fields of RNA translation and ribosome biology have demonstrated the heterogeneous nature of ribosomes. This manifests not only across different cellular contexts but also within the same cell. Such ...
  • Poison Center Surveillance of Occupational Incidents with Hazardous Materials (2016-2023): Insights for Risk Mitigation and Incident Preparedness 
    Wijnands, Anja P G; Koppen, Arjen; de Vries, Irma; de Lange, Dylan W; Rietjens, Saskia J (Multidisciplinary Digital Publishing Institute (MDPI), 2025-02)
    Incidents involving hazardous materials (HAZMAT incidents) can impact human health and the environment. For the development of risk mitigation strategies, it is essential to understand the circumstances of such incidents. ...
  • Irremediable Psychiatric Suffering, a Potential Indication for Psilocybin Treatment 
    Somers, Metten; Scheepers, Floortje E (American Psychiatric Association, 2025-03-01)
  • Ultra-Processed Food Consumption Is Associated With Poor Diet Quality and Nutrient Intake Among Adolescents in Urban Slums, Kenya 
    Wanjohi, Milkah N.; Asiki, Gershim; Wilunda, Calistus; Holdsworth, Michelle; Pradeilles, Rebecca; Paulo, Linda Simon; Langat, Nelson; Amugsi, Dickson A.; Kimenju, Simon; Kimani-Murage, Elizabeth W.; Klipstein-Grobusch, Kerstin (Frontiers Media S. A., 2025-03-05)
    Objectives: To assess the caloric contribution of ultra-processed foods (UPFs), factors associated with UPFs energy intake and investigate the relationship between UPFs energy intake, diet quality and nutrient intake among ...
  • Non-invasive imaging assessment in angina with non-obstructive coronary arteries (ANOCA) 
    Bergamaschi, Luca; De Vita, Antonio; Villano, Angelo; Tremamunno, Saverio; Armillotta, Matteo; Angeli, Francesco; Belmonte, Marta; Paolisso, Pasquale; Foà, Alberto; Gallinoro, Emanuele; Polimeni, Alberto; Sucato, Vincenzo; Morrone, Doralisa; Tuttolomondo, Domenico; Pavon, Anna Giulia; Guglielmo, Marco; Gaibazzi, Nicola; Mushtaq, Saima; Filardi, Pasquale Perrone; Indolfi, Ciro; Picano, Eugenio; Pontone, Gianluca; Lanza, Gaetano Antonio; Pizzi, Carmine; Coronary Physiopathology and Microcirculation Working Group of the Italian Society of Cardiology (SIC) (Mosby Inc., 2025-05)
    Due to its significant prevalence and clinical implications, angina with non-obstructive coronary arteries (ANOCA) has become a major focus in modern cardiology. In fact, diagnosing ANOCA presents a significant challenge. ...
  • Afadin loss induces breast cancer metastasis through destabilisation of E-cadherin to F-actin linkage 
    Rätze, Max Ak; Enserink, Lotte Nfl; Ishiyama, Noboru; van Kempen, Sven; Veltman, Christina Hj; Nijman, Isaac J; Haakma, Wisse E; Caldas, Carlos; Bernards, René; van Diest, Paul J; Christgen, Matthias; Koorman, Thijs; Derksen, Patrick Wb (John Wiley & Sons Inc., 2025-05)
    Afadin is a multimodal scaffolding protein with essential functions in cell–cell adhesion. Although its loss of expression has been linked to breast cancer invasion and metastasis, the underlying mechanisms driving tumour ...