Background: Early prediction of ICU death in acute hypoxemic respiratory failure (AHRF) could inform clinicians for targeting therapies to reduce harm and increase survival. We sought to determine clinical modifiable and ...

Objectives: To determine the presence and prognostic value of PD-L1 and PD-L2 expression, and tumor-infiltrating lymphocytes (TILs) in oral squamous cell carcinoma (OSCC) of non-smokers and non-drinkers (NSND). Materials ...

Background: Diagnosing fracture-related infection (FRI) without clinical confirmatory signs is challenging. [18F]FDG-PET/CT has been shown to have good diagnostic accuracy. However, direct interpretation criteria are ...

Background: The current standard therapy for pediatric optic pathway/hypothalamic glioma (OPHG) is systemic anticancer therapy (SAT) over surgery and radiotherapy. Nevertheless, recurrent radiological or clinical tumor ...

As the global population ages, so too does the prevalence of older people with chronic kidney disease (CKD). Helping people age well with CKD and supporting older people with end-stage kidney disease (ESKD) to make ...

The purpose of this study was to determine the independent association between placental inflammation and the development of retinopathy of prematurity (ROP). This retrospective cohort study included 591 neonates born with ...

BACKGROUND There are concerns whether (repeated) exposure to general anaesthesia is associated with long-term cognitive decline. OBJECTIVE We investigated the potential, negative relationship between total exposure to ...

Cell-type-specific gene activation is regulated by enhancers, sometimes located at large genomic distances from target gene promoters. Whether distal enhancers require specific factors to orchestrate gene regulation remains ...

OBJECTIVE: This study evaluates patient experiences with the SAFE@home platform for telemonitoring of blood pressure (BP) and symptom tracking in patients high-risk pregnancies. We hypothesized patients would perceive ...