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UMC Repository: Recent submissions

  • Associations of various medical nutrition therapy strategies with body composition, and physical and clinical outcomes in acute myeloid leukemia patients undergoing intensive remission-induction treatment: A multicenter prospective correlational study 
    van Lieshout, Rianne; Tick, Lidwine W; Beckers, Erik A M; Biesbroek, Willemijn; Custers, Stephanie; Dieleman, Jeanne P; Dijkstra, Myrthe; Groenesteijn, Wanda; Heldens, Aniek; Hengeveld, Martine M; Koene, Harry R; Kranenburg, Suzanne; van der Lee, Debbie; van der Put, Liesbeth; Rademakers, Nicky; Regelink, Josien C; Regis, Marta; Somer, Maaike; van Tilborg, Claudia J; Westerweel, Peter E; de Witte, Moniek; de Zeeuw, Sandra; Schouten, Harry C; Beijer, Sandra (Elsevier, 2025-06)
    BACKGROUND & AIMS: Medical nutrition therapy (MNT) is commonly used in patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) undergoing intensive remission-induction treatment to prevent malnutrition, ...
  • Objectifying Clinical Outcomes After Lymphaticovenous Anastomosis and Vascularized Lymph Node Transfer in the Treatment of Extremity Lymphedema: A Systematic Review and Meta-Analysis 
    Hahn, Brett A; Kleeven, Alieske; Richir, Milan C; Witkamp, Arjen J; Kuijpers, Anke M J; de Jong, Tim; Qiu, Shan; Coert, J Henk; Krijgh, David D (Wiley-Liss Inc., 2025-03)
    BACKGROUND: Upper extremity lymphedema (UEL) and lower extremity lymphedema (LEL) can develop as a result of lymph node dissection in the treatment of various malignancies. While emerging microsurgical interventions using ...
  • Rationale and design of the ILIAS ANOCA clinical trial: A blinded-arm controlled trial for routine ad-hoc coronary function testing 
    Boerhout, Coen K M; Namba, Hanae F; Liu, Tommy; Beijk, Marcel A M; Damman, Peter; Meuwissen, Martijn; Ong, Peter; Sechtem, Udo; Appelman, Yolande; Berry, Colin; Escaned, Javier; Lerman, Amir; Henry, Timothy D; van der Harst, Pim; Delewi, Ronak; Piek, Jan J; van de Hoef, Tim P (Mosby Inc., 2025-08)
    BACKGROUND: Angina with nonobstructive coronary arteries (ANOCA) is a major cause of chronic coronary syndromes, affecting nearly half of patients with anginal symptoms who undergo invasive coronary angiography. ANOCA may ...
  • The Role of Environmental Factors in Technology-Assisted Physical Activity Intervention Studies Among Older Adults: Scoping Review 
    Jansen, Carl-Philipp; Nijland, Désirée; Oppert, Jean-Michel; Alcan, Veysel; Keskinen, Kirsi E; Matikainen-Tervola, Emmi; Pajalic, Zada; Rantakokko, Merja; Tomsone, Signe; Tuomola, Essi-Mari; Portegijs, Erja; Timmermans, Erik J (JMIR Publications Inc., 2025-03-13)
    BACKGROUND: The rapidly emerging integration of both technological applications and environmental factors in physical activity (PA) interventions among older adults highlights the need for an overarching investigation. ...
  • Baseline clinical and MRI risk factors for hamstring reinjury showing the value of performing baseline MRI and delaying return to play: a multicentre, prospective cohort of 330 acute hamstring injuries 
    Zein, Muhammad Ikhwan; Mokkenstorm, Milo J.K.; Cardinale, Marco; Holtzhausen, Louis; Whiteley, Rod; Moen, Maarten H.; Reurink, Guus; Tol, Johannes L.; Almusa, Emad; Bahr, Roald; Bierma-Zeinstra, Sita M.A.; Boukarroum, Sirine; Buckens, Stan; Chalabi, Hakim; Eirale, Cristiano; Farooq, Abdulaziz; Froeling, Martijn; Geertsema, Celeste; Goudswaard, Gert Jan; Hamilton, Bruce; Hooijmans, Melissa T.; Maas, Mario; Monte, Jithsa R.; Nederveen, Aart J.; Oudeman, Jos; Smithuis, Frank F.; Strijkers, Gustav J.; Suskens, Jozef J.M.; Targett, Stephen; van der Made, Anne D.; van Dyk, Nicol; Verhaar, Jan A.N.; Vermeulen, Robin; Wangensteen, Arnlaug; Weir, Adam; Qatari and Dutch Hamstring Study Group (BMJ Publishing Group, 2024-07-01)
    Objectives Studies identifying clinical and MRI reinjury risk factors are limited by relatively small sample sizes. This study aimed to examine the association between baseline clinical and MRI findings with the incidence ...
  • Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk 
    Choi, Seung Hoan; Jurgens, Sean J; Xiao, Ling; Hill, Matthew C; Haggerty, Christopher M; Sveinbjörnsson, Garðar; Morrill, Valerie N; Marston, Nicholas A; Weng, Lu-Chen; Pirruccello, James P; Arnar, David O; Gudbjartsson, Daniel Fannar; Mantineo, Helene; von Falkenhausen, Aenne S; Natale, Andrea; Tveit, Arnljot; Geelhoed, Bastiaan; Roselli, Carolina; Van Wagoner, David R; Darbar, Dawood; Haase, Doreen; Soliman, Elsayed Z; Davogustto, Giovanni E; Jun, Goo; Calkins, Hugh; Anderson, Jeffrey L; Brody, Jennifer A; Halford, Jennifer L; Barnard, John; Hokanson, John E; Smith, Jonathan D; Bis, Joshua C; Young, Kendra; Johnson, Linda S B; Risch, Lorenz; Gula, Lorne J; Kwee, Lydia Coulter; Chaffin, Mark D; Kühne, Michael; Preuss, Michael; Gupta, Namrata; Nafissi, Navid A; Smith, Nicholas L; Nilsson, Peter M; van der Harst, Pim; Wells, Quinn S; Judy, Renae L; Schnabel, Renate B; Johnson, Renee; Smit, Roelof A J; Regeneron Genetics Center (Nature Research, 2025-03)
    Atrial fibrillation (AF) is a prevalent and morbid abnormality of the heart rhythm with a strong genetic component. Here, we meta-analyzed genome and exome sequencing data from 36 studies that included 52,416 AF cases and ...
  • Age and Latent Cytomegalovirus Infection Do Not Affect the Magnitude of De Novo SARS-CoV-2-Specific CD8+ T Cell Responses 
    van den Dijssel, Jet; Konijn, Veronique A L; Duurland, Mariël C; de Jongh, Rivka; Koets, Lianne; Veldhuisen, Barbera; Raaphorst, Hilde; Turksma, Annelies W; Freen-van Heeren, Julian J; Steenhuis, Maurice; Rispens, Theo; van der Schoot, C Ellen; van Ham, S Marieke; van Lier, Rene A W; van Gisbergen, Klaas P J M; Ten Brinke, Anja; van de Sandt, Carolien E (Wiley-VCH Verlag, 2025-03)
    Immunosenescence, age-related immune dysregulation, reduces immunity upon vaccinations and infections. Cytomegalovirus (CMV) infection results in declining naïve (Tnaïve) and increasing terminally differentiated (Temra) T ...
  • Cognitive impairment within and beyond the FTD spectrum in ALS: development of a complementary cognitive screen 
    Michielsen, Annebelle; van Veenhuijzen, Kevin; Hiemstra, Fenna; Jansen, Ilse M; Kalkhoven, Boaz; Veldink, Jan H; Kruitwagen, Esther T; van Es, Michael; van Zandvoort, Martine J E; van den Berg, Leonard H; Westeneng, Henk-Jan (Springer Science and Business Media Deutschland GmbH, 2025-03-13)
    OBJECTIVE: To investigate cognitive impairments in amyotrophic lateral sclerosis (ALS), extending both within and beyond the established frontotemporal dementia (FTD) spectrum, using the Complementary Cognitive ALS Screen ...
  • Advances in kidney biopsy lesion assessment through dense instance segmentation 
    Xiong, Zhan; He, Junling; Valkema, Pieter; Nguyen, Tri Q; Naesens, Maarten; Kers, Jesper; Verbeek, Fons J (Elsevier, 2025-06)
    Renal biopsies are the gold standard for the diagnosis of kidney diseases. Lesion scores made by renal pathologists are semi-quantitative and exhibit high inter-observer variability. Automating lesion classification within ...
  • Revisiting the Montreal Cognitive Assessment in a European cohort of elderly living with type 2 diabetes 
    Popovic, Natasa; Lois, Noemi; Pérez-Hoyos, Santiago; Simó, Rafael; Exalto, Lieza G; RECOGNISED Consortium (2025-03)
    BackgroundIndividuals with type 2 diabetes have an increased risk of developing both vascular and Alzheimer's dementia.ObjectiveThis prospective cross-sectional study assessed the screening ability of the standard Montreal ...
  • Long-term risk of endometrial cancer after assisted reproductive technology 
    Spaan, Mandy; van den Belt-Dusebout, Alexandra W; Lambalk, Cornelis B; van Boven, Hester; van Loendersloot, Laura L; Broekmans, Frank J M; Laven, Joop S E; van Santbrink, Evert J P; Nap, Annemiek W; van der Westerlaken, Lucette A J; Cohlen, Ben J; Cantineau, Astrid E P; Smeenk, Jesper M J; van Rumste, Minouche M; Goddijn, Mariëtte; van Golde, Ron J T; Meeuwissen, Paul A M; de Bruin, Jan P; Ouwens, Gabriële M; Gerritsma, Miranda A; Schaapveld, Michael; Burger, Curt W; van Leeuwen, Flora E (Oxford University Press, 2025-04)
    STUDY QUESTION: What is the risk of endometrial cancer after long-term follow-up in women treated with ART between 1983 and 2001 compared with women in the general population and subfertile women who did not undergo ART? ...
  • The relation between cerebral small vessel function and white matter microstructure in monogenic and sporadic small vessel disease - the ZOOM@SVDs study 
    Vlegels, Naomi; van den Brink, Hilde; Kopczak, Anna; Arts, Tine; Pham, Stanley D.T.; Siero, Jeroen C.W.; Gesierich, Benno; De Luca, Alberto; Duering, Marco; Zwanenburg, Jaco J.M.; Dichgans, Martin; Biessels, Geert Jan (Elsevier, 2025-01)
    In cerebral small vessel disease (cSVD), vascular dysfunction has been associated with cSVD-lesions across the brain. Here we further explore the relation between vascular dysfunction and cSVD-related brain injury. We ...
  • Long-term effects of telemonitoring on healthcare usage in patients with heart failure or COPD 
    van der Burg, Jorien M.M.; Aziz, N. Ahmad; Kaptein, Maurits C.; Breteler, Martine J.M.; Janssen, Joris H.; van Vliet, Lisa; Winkeler, Daniel; van Anken, Anneke; Kasteleyn, Marise J.; Chavannes, Niels H. (2020-01)
    Background: Heart failure and chronic obstructive pulmonary disease (COPD) are leading causes of disability and lead to substantial healthcare costs. The aim of this study was to evaluate the effectiveness of home ...
  • Development of a Decision Model to Estimate the Outcomes of Treatment Sequences in Advanced Melanoma 
    de Groot, Saskia; Blommestein, Hedwig M; Leeneman, Brenda; Uyl-de Groot, Carin A; Haanen, John B A G; Wouters, Michel W J M; Aarts, Maureen J B; van den Berkmortel, Franchette W P J; Blokx, Willeke A M; Boers-Sonderen, Marye J; van den Eertwegh, Alfons J M; de Groot, Jan Willem B; Hospers, Geke A P; Kapiteijn, Ellen; van Not, Olivier J; van der Veldt, Astrid A M; Suijkerbuijk, Karijn P M; van Baal, Pieter H M (SAGE Publications Inc., 2025-04)
    BackgroundA decision model for patients with advanced melanoma to estimate outcomes of a wide range of treatment sequences is lacking.ObjectivesTo develop a decision model for advanced melanoma to estimate outcomes of ...
  • The role of physical activity, sedentary behaviour, diet, adiposity and body composition on health-related quality of life and cancer-related fatigue after diagnosis of colorectal cancer: a Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis 
    Markozannes, G; Cividini, S; Aune, D; Becerra-Tomás, N; Kiss, S; Balducci, K; Vieira, R; Cariolou, M; Jayedi, A; Greenwood, D C; Brockton, N T; Croker, H; Mitrou, P; Copson, E; Renehan, A G; Bours, M; Demark-Wahnefried, W; Hudson, M M; May, A M; Odedina, F T; Skinner, R; Steindorf, K; Tjønneland, A; Velikova, G; Baskin, M L; Chowdhury, R; Hill, L; Lewis, S J; Seidell, J; Weijenberg, M P; Krebs, J; Cross, A J; Tsilidis, K K; Chan, D S M (Elsevier, 2025-04)
    BACKGROUND: The impact of physical activity, sedentary behaviour, diet, adiposity, and body composition on health-related quality of life (HRQoL) and cancer-related fatigue among colorectal cancer survivors remains uncertain. ...
  • Monitoring of child-specific activities in ambulatory children with and without developmental disabilities 
    Engels, Barbara; Bloemen, Manon A T; Felius, Richard; Damen, Karlijn; Bolster, Eline A M; Wittink, Harriët; Engelbert, Raoul H H; Gorter, Jan Willem (BioMed Central, 2025-03-15)
    BACKGROUND: Pediatric healthcare professionals facilitate children to enhance and maintain a physically active lifestyle. Activity monitors (AM) can help pediatric healthcare professionals assess physical activity in ...
  • Remote web-based self-assessment of visual acuity versus ETDRS in patients with macular diseases: a method comparison study 
    van der Zee, Casper; Huynh, Leon Daniel Huang; Imhof, Saskia Marijke; Ossewaarde-van Norel, Jeannette; van Leeuwen, Redmer; Wisse, Robert Pieter Leendert (2025-03-14)
    BACKGROUND: Macular diseases (MD) lead to frequent clinic visits, involve time-consuming visual acuity (VA) measurements by professionals. Independent home measurements could improve efficiency. This study evaluates the ...
  • Clinical standards in angina and non-obstructive coronary arteries: A clinician and patient consensus statement 
    Berry, Colin; Camici, Paolo G; Crea, Filippo; George, Maria; Kaski, Juan Carlos; Ong, Peter; Pepine, Carl J; Pompa, Annette; Sechtem, Udo; Shimokawa, Hiroaki; Zeitz, Christopher; Escaned, Javier; van de Hoef, Tim P; Beltrame, John F; Merz, C Noel Bairey; Coronary Vasomotor Disorders International Study (COVADIS) Group (Elsevier Ireland Ltd, 2025-06-15)
    Patients with angina and non-obstructive coronary arteries (ANOCA) or myocardial ischaemia with non-obstructive coronary arteries (INOCA) comprise a relatively large subgroup within those with ischaemic heart disease. ...
  • Acute toxicity and quality of life after margin reduction using a sub-fractionation workflow for stereotactic radiotherapy of localized prostate cancer on a 1.5 Tesla MR-linac 
    Lalmahomed, T A; Willigenburg, T; van de Pol, S M G; de Groot-van Breugel, E N; Snoeren, L M W; Hes, J; van Melick, H H E; Verkooijen, H M; de Boer, J C J; van der Voort van Zyp, J R N (Elsevier Ireland Ltd, 2025-06)
    BACKGROUND AND PURPOSE: A sub-fractionation workflow to correct for intrafraction motion in localized prostate cancer radiotherapy was implemented at our center, allowing for PTV margin reduction from isotropic 5 mm to 2 ...
  • Sex Differences in Acute Coronary Syndromes: A Scoping Review Across the Care Continuum 
    Marzà-Florensa, Anna; Kiss, Pauline; Youssef, Dina Mohamed; Jalali-Farahani, Sara; Lanas, Fernando; di Cesare, Mariachiara; González Juanatey, José Ramón; Taylor, Sean; Uijl, Alicia; Grobbee, Diederick E; Des Rosiers, Sarah; Perel, Pablo; Peters, Sanne A E (Elsevier Science & Technology, 2025-03-11)
    INTRODUCTION: Optimal diagnosis and management of acute coronary syndrome (ACS) is essential to improve clinical outcomes and prognosis. Sex disparities in ACS care have been reported in the literature, but evidence gaps ...