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Now showing items 1161-1180 of 40729

Use of maximal dosage renin-angiotensin-aldosterone system inhibitors in a real life population of complicated type 2 diabetes – contraindications and opportunities

Gant, C. M.; Oosterwijk, M. M.; Binnenmars, S. H.; Navis, G. J.; Haverkate, H.; Bakker, S. J.L.; Laverman, G. D. (BioMed Central, 2023-12)

Objective: Pharmacological inhibition of the renin-angiotensin-aldosterone-system (RAASi) is the cornerstone of hypertension treatment, renoprotection and secondary prevention of cardiovascular disease in patients with ...
Physical Activity and Symptom Burden in COPD: The Canadian Obstructive Lung Disease Study

Oostrik, Loes; Bourbeau, Jean; Doiron, Dany; Ross, Bryan; Zhi-Li, Pei; Aaron, Shawn D.; Chapman, Kenneth R.; Hernandez, Paul; Maltais, François; Marciniuk, Darcy D.; O’Donnell, Denis; Tan, Wan C.; Sin, Don D.; Walker, Brandie; Janaudis-Ferreira, Tania (COPD Foundation, 2023)

Background: The relationship between symptom burden and physical activity (PA) in chronic obstructive pulmonary disease (COPD) remains poorly understood with limited data on undiagnosed individuals and those with mild to ...
Regional, circuit and network heterogeneity of brain abnormalities in psychiatric disorders

Segal, Ashlea; Parkes, Linden; Aquino, Kevin; Kia, Seyed Mostafa; Wolfers, Thomas; Franke, Barbara; Hoogman, Martine; Beckmann, Christian F.; Westlye, Lars T.; Andreassen, Ole A.; Zalesky, Andrew; Harrison, Ben J.; Davey, Christopher G.; Soriano-Mas, Carles; Cardoner, Narcís; Tiego, Jeggan; Yücel, Murat; Braganza, Leah; Suo, Chao; Berk, Michael; Cotton, Sue; Bellgrove, Mark A.; Marquand, Andre F.; Fornito, Alex (Nature Research, 2023-09)

The substantial individual heterogeneity that characterizes people with mental illness is often ignored by classical case–control research, which relies on group mean comparisons. Here we present a comprehensive, multiscale ...
Capturing dynamics in nursing: a diary study of nurses’ job characteristics and ability and willingness to continue working

Vermeulen, Renée Cornelia Josephina Maria; van Leeuwen, Evelien Hanna (Frontiers Media S. A., 2023)

Objectives: This study aimed to gain insight into (1) the dynamics of job characteristics (demands and resources) of nurses and (2) how job characteristics relate to nurses’ ability and willingness to continue working ...
Spotlight on the 2024 ESC/EACTS management of atrial fibrillation guidelines: 10 novel key aspects

Rienstra, Michiel; Tzeis, Stylianos; Bunting, Karina V.; Caso, Valeria; Crijns, Harry J.G.M.; De Potter, Tom J.R.; Sanders, Prashanthan; Svennberg, Emma; Casado-Arroyo, Ruben; Dwight, Jeremy; Guasti, Luigina; Hanke, Thorsten; Jaarsma, Tiny; Lettino, Maddalena; Løchen, Maja Lisa; Lumbers, R. Thomas; Maesen, Bart; Mølgaard, Inge; Rosano, Giuseppe M.C.; Schnabel, Renate B.; Suwalski, Piotr; Tamargo, Juan; Tica, Otilia; Traykov, Vassil; Kotecha, Dipak; Van Gelder, Isabelle C. (Oxford University Press, 2024-12-01)

Atrial fibrillation (AF) remains the most common cardiac arrhythmia worldwide and is associated with significant morbidity and mortality. The European Society of Cardiology (ESC)/European Association for Cardio-Thoracic ...
Clinical and patient-reported outcomes after oncoplastic versus conventional breast conserving surgery-a longitudinal, multicenter cohort study

Bargon, Claudia A; Mink Van Der Molen, Dieuwke R; Young-Afat, Danny A; Batenburg, Marilot C T; Van Dam, Iris E; Baas, Inge O; Ernst, Miranda F; Maarse, Wiesje; Sier, Maartje F; Schoenmaeckers, Ernst J P; Burgmans, Josephina P J; Bijlsma, Rhodé M; Siesling, Sabine; Rakhorst, Hinne A; Mureau, Marc Am; Van Der Leij, Femke; Doeksen, Annemiek; Verkooijen, Helena M; UMBRELLA Study Group (Oxford University Press, 2025-04-01)

BACKGROUND: Oncoplastic breast conserving surgery (OP-BCS) is becoming increasingly popular to avoid mastectomy or optimize cosmetic outcomes of breast conserving surgery (BCS). Few studies have compared clinical outcomes ...
Artificial Intelligence and Predictive Modeling in Spinal Oncology: A Narrative Review

Kuijten, Rene Harmen; Zijlstra, Hester; Groot, Olivier Quinten; Schwab, Joseph Hasbrouck (Elsevier USA, 2023-06-01)

Background: Artificial intelligence (AI) tremendously influences our daily lives and the medical field, changing the scope of medicine. One of the fields where AI, and, in particular, predictive modeling, holds great promise ...
Antipsychotic medication for women with schizophrenia spectrum disorders - CORRIGENDUM

Brand, Bodyl A.; Haveman, Yudith R.A.; de Beer, Franciska; de Boer, Janna N.; Dazzan, Paola; Sommer, Iris E.C. (Cambridge University Press, 2023-07-01)
Maintenance Chemotherapy for Patients with Rhabdomyosarcoma

Bisogno, Gianni; Minard-Colin, Veronique; Jenney, Meriel; Ferrari, Andrea; Chisholm, Julia; Di Carlo, Daniela; Hjalgrim, Lisa Lyngsie; Orbach, Daniel; Merks, Johannes Hendrikus Maria; Casanova, Michela (Multidisciplinary Digital Publishing Institute (MDPI), 2023-08)

Maintenance chemotherapy (MC) defines the administration of prolonged relatively low-intensity chemotherapy with the aim of “maintaining” tumor complete remission. This paper aims to report an update of the RMS2005 trial, ...
Evaluation of Potential Targets for Fluorescence-Guided Surgery in Pediatric Ewing Sarcoma: A Preclinical Proof-of-Concept Study

Jeremiasse, Bernadette; Rijs, Zeger; Angoelal, Karieshma R.; Hiemcke-Jiwa, Laura S.; de Boed, Ella A.; Kuppen, Peter J.K.; Sier, Cornelis F.M.; van Driel, Pieter B.A.A.; van de Sande, Michiel A.J.; Wijnen, Marc H.W.A.; Rios, Anne C.; van der Steeg, Alida F.W. (Multidisciplinary Digital Publishing Institute (MDPI), 2023-08)

Fluorescence-guided surgery (FGS), based on fluorescent tracers binding to tumor-specific biomarkers, could assist surgeons to achieve complete tumor resections. This study evaluated potential biomarkers for FGS in pediatric ...
Technologies in Home-Based Digital Rehabilitation: Scoping Review

Arntz, Angela; Weber, Franziska; Handgraaf, Marietta; Lällä, Kaisa; Korniloff, Katariina; Murtonen, Kari Pekka; Chichaeva, Julija; Kidritsch, Anita; Heller, Mario; Sakellari, Evanthia; Athanasopoulou, Christina; Lagiou, Areti; Tzonichaki, Ioanna; Salinas, Iosune; Martínez-Bueso, Pau; Velasco-Roldán, Olga; Schulz, Ralf Joachim; Grüneberg, Christian (JMIR Publications Inc., 2023)

Background: Due to growing pressure on the health care system, a shift in rehabilitation to home settings is essential. However, efficient support for home-based rehabilitation is lacking. The COVID-19 pandemic has further ...
Impact of a Treatment Guide on Intravenous Fluids in Minimising the Risk of Hospital-Acquired Hyponatraemia in Denmark

Sindahl, Per; Overgaard-Steensen, Christian; Wallach-Kildemoes, Helle; De Bruin, Marie Louise; Kemp, Kaare; Gardarsdottir, Helga (Multidisciplinary Digital Publishing Institute (MDPI), 2023-08)

Hypotonic intravenous (IV) fluids are associated with an increased risk of hospital-acquired hyponatraemia, eventually leading to brain injury and death. We evaluated the effectiveness of a treatment guide to improve ...
Low-Threshold-For-Surgery Versus Primarily-Conservative Treatment for Odontoid Fractures in the Elderly: Evaluating Practice Variation in The Netherlands

Huybregts, Jeroen G.J.; Polak, Samuel B.; Jacobs, Wilco C.H.; Krekels-Huijbregts, Ilse A.; Smeets, Anouk Y.J.M.; Arts, Mark P.; Slooff, Willem Bart M.; Öner, F. Cumhur; Peul, Wilco C.; van Santbrink, Henk; Vleggeert-Lankamp, Carmen L.A. (SAGE Publications Inc., 2025-03)

Study Design: Retrospective cohort study. Objectives: Odontoid fractures are the most common cervical spine fractures in the elderly. The optimal treatment remains controversial. The aim of this study was to compare results ...
Impact of cardiac history and myocardial scar on increase of myocardial perfusion after revascularization

Jukema, Ruurt A.; de Winter, Ruben W.; Hopman, Luuk H.G.A.; Driessen, Roel S.; van Diemen, Pepijn A.; Appelman, Yolande; Twisk, Jos W.R.; Planken, R. Nils; Raijmakers, Pieter G.; Knaapen, Paul; Danad, Ibrahim (Springer-Verlag, 2023-11)

Purpose: We sought to assess the impact of coronary revascularization on myocardial perfusion and fractional flow reserve (FFR) in patients without a cardiac history, with prior myocardial infarction (MI) or non-MI ...
Recruitment and retention challenges and strategies in randomized controlled trials of psychosocial interventions for children with cancer and their parents: a collective case study

van Driessche, Anne; Beernaert, Kim; Deliens, Luc; Kars, Marijke C.; Lyon, Maureen E.; Barrera, Maru; Dussel, Veronica; Bidstrup, Pernille; Rosenberg, Abby R.; Akard, Terrah F.; Cohen, Joachim; De Vleminck, Aline (Springer-Verlag, 2023-10)

In pediatric oncology there are few examples of successful recruitment and retention strategies in psychosocial care research. This study aims to summarize experiences, challenges, and strategies for conducting randomized ...
Handling related publications reporting real-world evidence in network meta-analysis: a case study in multiple sclerosis

Betts, Marissa; Fahrbach, Kyle; Neupane, Binod; Slim, Mahmoud; Sormani, Maria Pia; Cutter, Gary; Debray, Thomas P.A.; Rock, Marvin (Future Medicine Ltd., 2023)

Aim: The presence of two or more publications that report on overlapping patient cohorts poses a challenge for quantitatively synthesizing real-world evidence (RWE) studies. Thus, we evaluated eight approaches for handling ...
Inter-pregnancy interval and associated factors among parous women in neighboring low-land ecologies of arsi & east shoa zone, southeast Ethiopia: a community-based cross-sectional study

Jima, Gebi Husein; Biesma, Regien; Sendekie, Tegbar Yigzaw; Stekelenburg, Jelle (BioMed Central Ltd., 2025-01-03)

BACKGROUND: The World Health Organization (WHO) recommends an interval of at least 24 months from the date of a live birth to the conception of the next pregnancy in order to reduce the risk of adverse maternal, perinatal, ...
Reply to Bouva et al. Comment on "Dijkstra et al. A False-Negative Newborn Screen for Tyrosinemia Type 1-Need for Re-Evaluation of Newborn Screening with Succinylacetone. Int. J. Neonatal Screen. 2023, 9, 66".

Dijkstra, Allysa M; Evers-van Vliet, Kimber; Heiner-Fokkema, M Rebecca; Bodewes, Frank A J A; Bos, Dennis K; Zsiros, József; van Aerde, Koen J; Koop, Klaas; van Spronsen, Francjan J; Lubout, Charlotte M A (Multidisciplinary Digital Publishing Institute (MDPI), 2024-12)

We thank the authors for their comments [...].
Duration of Antibiotic Treatment for Foot Osteomyelitis in People with Diabetes

Gramberg, Meryl Cinzía Tila Tamara; Torensma, Bart; van Asten, Suzanne; Sieswerda, Elske; Sabelis, Louise Willy Elizabeth; den Heijer, Martin; de Vries, Ralph; de Groot, Vincent; Peters, Edgar Josephus Gerardus (Multidisciplinary Digital Publishing Institute (MDPI), 2024-12)

Background: The optimal antimicrobial treatment duration for diabetes-related foot osteomyelitis (DFO) currently needs to be determined. We systematically reviewed the effects of short and long treatment durations on ...
Exploring Tutors’ Roles in Supporting Student Mental Health: Expectations and Perceptions in Higher Education

Douwes, Rynke; Metselaar, Janneke; van der Meulen, Erik; Boonstra, Nynke; Pijnenborg, Gerdina Hendrika Maria (Multidisciplinary Digital Publishing Institute (MDPI), 2024-12)

Student mental health is a challenging topic in higher education, with institutions aiming to develop policies and practices to support students’ personal and professional development. This study examined students’ ...

Now showing items 1161-1180 of 40729