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UMC Repository: Recent submissions

  • Food Environments and Diet Quality Among Vendors and Consumers in Five Traditional Urban Markets in Kenya 
    Demmler, Kathrin M.; van der Steen, Sophie; Trevenen-Jones, Ann; de Kanter, Emilie (Multidisciplinary Digital Publishing Institute (MDPI), 2025-01)
    Background/Objectives: Traditional food markets are essential in urban food environments in Kenya and other low- and middle-income countries (LMICs). They provide affordable fresh food, particularly for low-income urban ...
  • Mouse strain-specific responses along the gut-brain axis upon fecal microbiota transplantation from children with autism 
    Prince, Naika; Peralta Marzal, Lucia N.; Roussin, Léa; Monnoye, Magali; Philippe, Catherine; Maximin, Elise; Ahmed, Sabbir; Salenius, Karoliina; Lin, Jake; Autio, Reija; Adolfs, Youri; Pasterkamp, R. Jeroen; Garssen, Johan; Naudon, Laurent; Rabot, Sylvie; Kraneveld, Aletta D.; Perez-Pardo, Paula; On behalf of the GEMMA Consortium (Landes Bioscience, 2025)
    Several factors are linked to the pathophysiology of autism spectrum disorders (ASD); however, the molecular mechanisms of the condition remain unknown. As intestinal problems and gut microbiota dysbiosis are associated ...
  • Effects of POPs-induced SIRT6 alteration on intestinal mucosal barrier function: A comprehensive review 
    Chen, Guangcan; Huang, Tengyang; Dai, Yifeng; Huo, Xia; Xu, Xijin (Academic Press, 2025-01-01)
    Persistent organic pollutants (POPs) are pervasive organic chemicals with significant environmental and ecological ramifications, extending to adverse human health effects due to their toxicity and persistence. The intestinal ...
  • Prognostic Value of Molecular Aberrations in Low- or Intermediate-Risk Neuroblastomas: A Systematic Review 
    Bruinsma, Rixt S.; Lekkerkerker, Caroline W.M.; Fiocco, Marta; Dierselhuis, Miranda P.; Langenberg, Karin P.S.; Tytgat, Godelieve A.M.; van Noesel, Max M.; Wijnen, Marc H.W.A.; van der Steeg, Alida F.W.; de Krijger, Ronald R. (Multidisciplinary Digital Publishing Institute (MDPI), 2025-01)
    Background: The 5-year prognosis of non-high-risk neuroblastomas is generally good (>90%). However, a proportion of patients show progression and succumb to their disease. We aimed to identify molecular aberrations (not ...
  • New gantry angle-dependent beam control optimization with Elekta linear accelerator for VMAT delivery 
    van Appeldoorn, Adriaan Abraham; Kok, Johannes Gerardus Maria; Wolthaus, Jochem Willem Heiko (John Wiley & Sons Inc., 2025-03)
    Introduction: This paper describes a method to improve gantry-dependent beam steering for Elekta traveling wave linear accelerators by applying the measured and filtered beam servo corrections to the existing lookup table ...
  • Epidemiology of invasive Escherichia coli disease in adults in England, 2013–2017 
    Blum, Maxim; Geurtsen, Jeroen; Herweijer, Eva; Sarnecki, Michal; Spiessens, Bart; Diogo, Gil Reynolds; Hermans, Peter; Thelwall, Simon; Bhattacharya, Alex; Verstraeten, Thomas; Poolman, Jan; Hope, Russell (Cambridge University Press, 2025-01-06)
    Extraintestinal pathogenic Escherichia coli (ExPEC) causes invasive E. coli disease (IED), including bacteraemia and (uro)sepsis, resulting in a high disease burden, especially among older adults. This study describes the ...
  • Multiple Perspectives on the Need for Real-World Evidence to Inform Regulatory and Health Technology Assessment Decision-Making: Scoping Review and Stakeholder Interviews 
    Jansen, Marieke S.; Dekkers, Olaf M.; le Cessie, Saskia; Hooft, Lotty; Gardarsdottir, Helga; de Boer, Anthonius; Groenwold, Rolf H.H. (John Wiley & Sons Inc., 2025-01)
    Purpose: Real-world evidence (RWE) is increasingly considered in regulatory and health technology assessment (HTA) decision-making, though perspectives on its relevance may vary. Expanding on a recent review regarding ...
  • Introduction of Ivacaftor/Lumacaftor in Children With Cystic Fibrosis Homozygous for F508del in the Netherlands: A Nationwide Real-Life Study 
    Zwitserloot, A. M.; Aziz, S. Z.; Chen, Y.; Bannier, M. A.G.E.; Janssens, H. M.; Merkus, P. F.J.M.; Nuijsink, M.; Terheggen-Lagro, S. W.J.; Tiddens, H. A.W.M.; Zomer- van Ommen, D. D.; Vonk, J. M.; de Winter- de Groot, K. M.; Willemse, B. W.M.; Koppelman, G. H. (John Wiley & Sons Inc., 2025-01)
    Introduction: Lumacaftor/ivacaftor (lum/iva) was introduced in the Netherlands in 2017. We investigated 1-year efficacy of lum/iva on lung function and small airway and structural lung disease evaluated by multiple breath ...
  • Guidance for clinical management of pathogenic variant carriers at elevated genetic risk for ALS/FTD 
    Benatar, Michael; Heiman-Patterson, Terry D.; Cooper-Knock, Johnathan; Brickman, Daniel; Casaletto, Kaitlin B.; Goutman, Stephen A.; Vinceti, Marco; Dratch, Laynie; Arias, Jalayne J.; Swidler, Jean; Turner, Martin R.; Shefner, Jeremy; Westeneng, Henk Jan; van den Berg, Leonard H.; Al-Chalabi, Ammar; Attendees of the Workshop on Guidance for Clinical Care of People Living with a Pathogenic Variant At-Risk for ALS and FTD (BMJ Publishing Group, 2025-03-13)
    There is a growing understanding of the presymptomatic stages of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) and nascent efforts aiming to prevent these devastating neurodegenerative diseases have ...
  • EULAR points to consider for patient education in physical activity and self-management of pain during transitional care 
    Courel-Ibáñez, Javier; Prieto-Moreno, Rafael; Briones-Vozmediano, Erica; Ariza-Vega, Patrocinio; Angevare, Saskya; Anton, Jordi; Bini, Ilaria; Clemente, Daniel; Correia, Matilde; Costello, Wendy; De Cock, Diederik; Domján, Andrea; Leon, Leticia; Marques, Andréa; Minden, Kirsten; Mourão, Ana Filipa; Najm, Aurélie; Ozen, Seza; Pimentel, Georgina; Saleem, Zainab; Vetrovsky, Tomas; Wulffraat, Nico M.; Crovato, Andrea Zacarias; Prior, Yeliz; Carmona, Loreto; Estévez-López, Fernando (Elsevier, 2025-04)
    Objectives A EULAR task force was convened to develop points to consider (PtC) for patient education in physical activity and self-management of pain in young people with juvenile-onset rheumatic and musculoskeletal diseases ...
  • Toward a Generative Model for Emotion Dynamics 
    Ryan, Oisín; Dablander, Fabian; Haslbeck, Jonas M.B. (American Psychological Association, 2025-03)
    Most theories of emotion suggest that emotions are reactions to situations we encounter in daily life. Process theories of emotion further specify a feedback loop between our environment, attention, emotions, and action ...
  • Prostate-specific Membrane Antigen Positron Emission Tomography Before Reaching the Phoenix Criteria for Biochemical Recurrence of Prostate Cancer After Radiotherapy: Earlier Detection of Recurrences 
    van Altena, Evelien J E; Jansen, Bernard H E; Korbee, Marieke L; Knol, Remco J J; Luining, Wietske I; Nieuwenhuijzen, Jakko A; Oprea-Lager, Daniela E; van der Pas, Stéphanie L; van der Voort van Zyp, Jochem R N; van der Zant, Friso M; van Leeuwen, Pim J; Wondergem, Maurits; Vis, André N (Elsevier, 2025-04)
    BACKGROUND AND OBJECTIVE: Biochemical recurrence (BCR) of prostate cancer (PCa) after curative radiotherapy (RT) is defined according to the Phoenix criteria, which is a prostate-specific antigen (PSA) rise of ≥2.0 ng/ml ...
  • ASO Author Reflections: Liver Failure Dominates the Risk of Failure to Rescue After Surgery for Perihilar Cholangiocarcinoma 
    Olthof, Pim B.; Bouwense, Stefan A.W.; Dewulf, Maxime; Olde Damink, Steven W.M.; Neumann, Ulf P.; Koerkamp, Bas Groot; Molenaar, Q. I.; Hagendoorn, J.; on behalf of the Perihilar Cholangiocarcinoma Collaboration Group (Springer New York, 2025-03)
  • ASO Author Reflections: Surgical Strategy for Perihilar Cholangiocarcinoma 
    Olthof, Pim B.; Groot Koerkamp, Bas; the Perihilar Cholangiocarcinoma Collaboration Group (Springer New York, 2024-07)
  • Pre-emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant recipients 
    Vernooij, Robin Wm; Michael, Mini; Colombijn, Julia Mt; Owers, Daniel S; Webster, Angela C; Strippoli, Giovanni Fm; Hodson, Elisabeth M (John Wiley & Sons Inc., 2025-01-14)
    BACKGROUND: Cytomegalovirus (CMV) is a significant cause of morbidity and death in solid organ transplant recipients. Pre-emptive treatment of patients with CMV viraemia using antiviral agents has been suggested as an ...
  • Importance of early use of tolvaptan in hyponatremic acutely decompensated heart failure patients, a retrospective study 
    Soerarso, Rarsari; Yonas, Emir; Sirait, Silfi Pauline; Hasanah, Dian Yaniarti; Raharjo, Sunu Budhi; Siswanto, Bambang Budi; Cramer, Maarten J; van der Harst, Pim; Oerlemans, Marish I F J (Springer Science and Business Media Deutschland GmbH, 2025-01-13)
    BACKGROUND: Hyponatremia is one of the complicating findings in acute decompensated heart failure. Decrease in cardiac output and systemic blood pressure triggers activation of renin-angiotensin-aldosterone system, ...
  • Contemporary Use of Post-Dilatation for Stent Optimization During Percutaneous Coronary Intervention; Results From the Netherlands Heart Registration 
    van Beek, K A J; Timmermans, M J C; Derks, L; Cheng, J M; Kraaijeveld, A O; Arkenbout, E K; Schotborgh, C E; Brouwer, J; Claessen, B E; Lipsic, E; Polad, J; van Nunen, L X; Sjauw, K; van Veghel, D; Tonino, P A; Teeuwen, K; ‘on behalf of the PCI registration committee of The Netherlands Heart Registration’ (John Wiley & Sons Inc., 2025-03)
    BACKGROUNDS: Post-dilatation after stenting with a non-compliant (NC) balloon can be used to improve overall percutaneous coronary intervention (PCI) result. Due to lack of evidence on the effect of post-dilatation on ...
  • Three-Dimensional Rotational Angiography to Guide Cardiac Catheterization in Critical Infants Below 5kg of Body Weight 
    Lucas, Chenise N; Slieker, Martijn G; Molenschot, Mirella M C; Breur, Hans M P J; Krings, Gregor J (Elsevier, 2024-12)
    Background: Three-dimensional rotational angiography (3DRA) is a promising advancement to guide cardiac catheterizations. It is used with restraint in critically ill infants with congenital heart disease (CHD) due to the ...
  • ePlatypus: an ecosystem for computational analysis of immunogenomics data 
    Cotet, Tudor-Stefan; Agrafiotis, Andreas; Kreiner, Victor; Kuhn, Raphael; Shlesinger, Danielle; Manero-Carranza, Marcos; Khodaverdi, Keywan; Kladis, Evgenios; Desideri Perea, Aurora; Maassen-Veeters, Dylan; Glänzer, Wiona; Massery, Solène; Guerci, Lorenzo; Hong, Kai-Lin; Han, Jiami; Stiklioraitis, Kostas; D'Arcy, Vittoria Martinolli; Dizerens, Raphael; Kilchenmann, Samuel; Stalder, Lucas; Nissen, Leon; Vogelsanger, Basil; Anzböck, Stine; Laslo, Daria; Bakker, Sophie; Kondorosy, Melinda; Venerito, Marco; Sanz García, Alejandro; Feller, Isabelle; Oxenius, Annette; Reddy, Sai T; Yermanos, Alexander (Oxford University Press, 2023-09-02)
    Motivation: The maturation of systems immunology methodologies requires novel and transparent computational frameworks capable of integrating diverse data modalities in a reproducible manner. Results: Here, we present the ...
  • Burden of RSV infections among young children in primary care: a prospective cohort study in five European countries (2021-23) 
    Hak, Sarah F; Sankatsing, Valérie D V; Wildenbeest, Joanne G; Venekamp, Roderick P; Casini, Beatrice; Rizzo, Caterina; Bangert, Mathieu; Van Brusselen, Daan; Button, Elizabeth; Garcés-Sánchez, María; Vera, César García; Kramer, Rolf; de Lusignan, Simon; Raes, Marc; Meijer, Adam; Paget, John; van Summeren, Jojanneke; RSV ComNet Network (Elsevier Limited, 2025-02)
    Background: The majority of respiratory syncytial virus (RSV) infections in young children are managed in primary care, however, the disease burden in this setting remains poorly defined. Methods: We did a prospective ...