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Utrecht University Repository: Recent submissions

Now showing items 61-80 of 95693

On strangleholds and tipping points: Transmission dynamics of Streptococcus equi subspecies equi and equine herpesvirus 1

Houben, Rosa Maria Allegonda Catharina (Utrecht University, 2024-09-03)

The infectious agents Streptococcus equi subspecies equi (S. equi, the cause of strangles) and EHV-1 (a cause of mild cold-like symptoms, but also of abortion and neurological disease) occur frequently in horses in the ...
Exploring the potential of Aspergillus vadensis and Penicillium subrubescens as enzyme cell factories

Liu, Dujuan (Utrecht University, 2024-09-24)

This thesis aims to understand the regulation of plant biomass degradation in promising cell factory candidates such as Aspergillus vadensis and Penicillium subrubescens and capitalize on this knowledge to develop them ...
Hydraulic parameter estimation of saturated sand using silica encapsulated, DNA tagged microparticles: - Laboratory experiments and numerical modeling

Chakraborty, Swagatam (Utrecht University, 2024-06-17)

Determining hydraulic parameters of aquifers, their associated uncertainties and spatio-temporal variation is important to characterize groundwater flow and mass transport. Of these hydraulic parameters, hydraulic conductivity, ...
Nanobody-conjugated nanoparticles for photodynamic therapy: steps towards a targeted therapy for cholangiocarcinoma

Maia Mesquita, Bárbara Sofia (Utrecht University, 2024-09-16)

The aim of this work was to develop stable nanoparticles (NPs) for the systemic delivery of both hydrophobic and hydrophilic phthalocyanines that could improve specific accumulation of these photosensitizers (PS) in the ...
Embodied Performances of Forensic Expertise: Epistemic Virtues, Gender, and Emotions in British Forensic Culture 1920-1980

Dirven, Paulina Emilia Anna Maria (Utrecht University, 2024-09-06)

Today, it is obvious that the services of scientists and medical practitioners are required to solve a crime. When you watch crime series on television, the presence of a CSI team and pathologist is self-evident, as is ...
Preparing health professions learners to work with uncertainty

Moffett, Jennifer Elizabeth (Utrecht University, 2024-09-11)

The overarching aim of this PhD thesis is to investigate how health professions students learn to manage uncertainty during their undergraduate training. The work focusses in particular on the potential of an innovative ...
Sources and biogeochemistry of bio-active trace metals in the Southern Ocean and coastal Antarctica: perspectives from their isotopes

Tian, Hung-An (Utrecht University, 2024-03-15)

Bio-essential trace elements, such as iron (Fe) and zinc (Zn), also known as micronutrients, are critical for all life because of their biochemical roles in various metabolic processes. They are also pivotal for marine ...
Exploring Relationships among Topics in Neuroscience Literature using Augmented Reality Visualization

Tanhaei, Ghazaleh (Utrecht University, 2024-08-30)

Neuroscience researchers frequently consult scholarly articles to guide their experimental inquiries, primarily aiming to identify potential new experiments. To determine viable experiments, neuroscientists must understand ...
Late Quaternary East Asian Monsoon precipitation dynamics and vegetation response on the Chinese Loess Plateau

Fuchs, Louise (Utrecht University, 2024-09-19)

Research on climate change has intensified after the IPCC warned about more extreme weather events due to global warming, threatening the environment and human life. In East Asia, the climate is influenced by the East Asian ...
Quantitative reconstruction of late Quaternary climate in monsoonal East Asia: Validation and application of tetraether membrane lipid proxies and clumped isotope thermometry

Guo, Jingjing (Faculty of Geosciences, Utrecht University, 2024-09-20)

The East Asian Monsoon (EAM) is one of the strongest monsoon systems and controls the water supply to over 20% of the world’s population. Theoretically, the EAM will strengthen in response to ongoing global warming, however, ...
The exposome puzzle: advanced statistical methods for investigating the contextual determinants of cardiometabolic diseases

Ohanyan, Haykanush (Utrecht University, 2024-09-06)

Obesity is a chronic condition that leads to a range of other non-communicable diseases, including type 2 diabetes (T2D). In recent decades, the incidence rates of obesity and T2D have risen alarmingly, posing a significant ...
Oordelen zonder oogkleppen: De rol van het informatieproces in de kwaliteit van oordelen door toezichthouders in semipublieke organisaties

Duran, Mehmet (Utrecht University, 2024-10-25)

Semi-public organizations play an important role in public services in the Netherlands. Citizens rely on their services throughout their lives, including healthcare, culture, childcare, education, and housing. Supervisory ...
Macrocyclic peptide inhibitors of viral fusion proteins

Thijssen, Vito (Utrecht University, 2024-09-25)

Pandemic outbreaks of viruses present a significant global challenge, necessitating continuous updates to vaccines and exploration of new antiviral drugs. This thesis explores a strategy targeting the coat glycoproteins ...
QUANTIFYING TACIT KNOWLEDGE: Assessing the evolution of tacit knowledge in the production of salt in the Low Countries (1000-2000)

Veij, Willem de (Utrecht University, 2024-09-27)

Regularly, results of studies on the number of jobs available in the near future appear in the media. The conclusions are often alarming when it turns out that a large number of jobs will disappear in the long term. The ...
Genes involved in growth and sporulation in Aspergillus niger

Chen, Xiaoyi (Utrecht University, 2024-09-12)

Aspergillus niger breaks down organic waste in nature, is a pathogen of plants and animals, but can also make a positive contribution to the growth of plants. This fungus is also a human pathogen and spoils food, but on ...
From compact greens to ascending stems: elucidating the role of ATH1 in regulating internode growth dynamics in Arabidopsis thaliana

Shokrian Hajibehzad, Shahram (Utrecht University, 2024-09-09)

This thesis investigates the mechanisms underlying rosette initiation and robustness, as well as bolting regulation in Arabidopsis thaliana with an emphasis on ATH1’s role. Chapter 2: This chapter investigates the ...
Breed-related tumours in Bernese mountain dogs and Flat-coated retrievers and the predisposition to Histiocytic Sarcoma

Erich, Suzanne Agnes (Utrecht University, 2024-09-26)

The high prevalence of histiocytic sarcoma (HS), one of the most aggressive and still nearly always fatal tumours, in the Bernese mountain dog (BMD) and the Flat-coated retriever (FCR), leads to increasing concern among ...
Influenza A Virus Infection: Thriving on Receptor Diversity

Liu, Mengying (Utrecht University, 2024-09-09)

To enter a cell, a virus must bind to a receptor. Influenza A virus (IAV) attaches to sialic acids (Sia) on glycan chains. IAV binding requires multivalent binding due to the low binding affinity of protein-glycan interactions. ...
Branch-and-bound trees, integrality gaps and online optimization: A tale of algorithms and randomness

Borst, Sander Johannes (Utrecht University, 2024-08-27)

Optimization problems are everywhere: from creating high school timetables to designing computer chips. Many such problems can be reduced to one single generic type of problem, called a mixed-integer-program (MIP). For ...
A Symphony of Noise in Nonlinear Optical Resonators

Peters, Kevin Jean Hubertus (Utrecht University, 2024-09-04)

Understanding the effect of noise on light’s behavior is crucial, as light plays a central role in the study of many systems. This thesis explores the interplay between light, matter, and noise, demonstrating how this ...

Now showing items 61-80 of 95693