Abstract
Facioscapulohumeral muscular dystrophy (FSHD) is a muscle degenerative disease that disproportionally affects the muscles of the face, shoulder girdle and upper arms. FSHD is caused by the ectopic expression of Double Homeobox 4 (DUX4), which has been derepressed due to aberrant genetic and epigenetic events. DUX4 expression is normally tightly
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