A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells

Ressa, Anna; Bosdriesz, Evert; de Ligt, Joep; Mainardi, Sara; Maddalo, Gianluca; Prahallad, Anirudh; Jager, Myrthe; de la Fonteijne, Lisanne; Fitzpatrick, Martin; Groten, Stijn; Altelaar, A. F. Maarten; Bernards, Rene; Cuppen, Edwin; Wessels, Lodewyk; Heck, Albert J. R.

doi:https://doi.org/10.1074/mcp.RA117.000486

A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells

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A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells

Ressa, Anna; Bosdriesz, Evert; de Ligt, Joep; Mainardi, Sara; Maddalo, Gianluca; Prahallad, Anirudh; Jager, Myrthe; de la Fonteijne, Lisanne; Fitzpatrick, Martin; Groten, Stijn; Altelaar, A. F. Maarten; Bernards, Rene; Cuppen, Edwin; Wessels, Lodewyk; Heck, Albert J. R.

(2018) Molecular & Cellular Proteomics, volume 17, issue 10, pp. 1892 - 1908

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Keywords: Colorectal cancer, Drug resistance, Systems biology, Signaling, Circuits, Transcription, BRAF(V600E), EGFR, PTPN11, Rintegrative analysis, multi-omics

DOI: https://doi.org/10.1074/mcp.RA117.000486

ISSN: 1535-9476

Publisher: American Society for Biochemistry and Molecular Biology Inc.

(Peer reviewed)