Lessons learned from PIAMA - Critical review - The impact of overweight on asthma

Abstract

The association between increased risk of asthma and overweight has substantial evidence, though this association at different stages of life and the mechanisms involved are not clear. The aim of this thesis is to make a critical review and an in depth discussion of the overall findings from the Prevention and Incidence of Asthma and Mite Allergy study (PIAMA), that investigates the association between overweight and asthma with a particular focus at the prenatal, perinatal and postnatal factors influencing the development of asthmatic symptoms. The thesis would start with an introduction to asthma as a disease, followed by the methods describing the study population and measures of the overweight and measures of asthma as done in the PIAMA and a critical review of the papers on overweight and asthma in PIAMA study, ending with the results and discussion.